中国耳鼻咽喉头颈外科2025，Vol.32Issue(2)：76-81,6.DOI:10.16066/j.1672-7002.2025.02.003
衰老对视听双任务大脑信号变异性的影响
The effect of aging on brain signal variability in visual-audio dual tasks
摘要
Abstract
OBJECTIVE Exploring the specific changes in brain signal variability during healthy aging using functional near-infrared spectroscopy technology.METHODS Twenty-eight young adults and 30 elderly adults were included,and functional near-infrared spectroscopy was used to record the changes in brain blood oxygen and calculate the brain signal variability during the execution of visual-audio dual tasks.RESULTS The brain signal variability of the elderly group was significantly reduced when performing visual-audio dual tasks,especially in the bilateral dorsolateral prefrontal cortex,right Broca,bilateral primary somatosensory cortex,bilateral Wernicke area,bilateral frontopolar area,bilateral primary motor cortex,bilateral somatosensory association cortex,bilateral orbitofrontal area,bilateral pre-motor and supplementary motor cortex.The brain signal variability in the left primary somatosensory cortex(r=-0.385,P=0.043)and right primary somatosensory cortex(r=-0.386,P=0.042)of young adults was negatively correlated with visual reaction time;The brain signal variability in the right somatosensory association cortex(r=-0.371,P=0.044),left pre-motor and supplementary motor cortex(r=-0.393,P=0.032)of elderly adults was negatively correlated with visual reaction time.CONCLUSION Elderly individuals exhibit a significant reduction in neural signal variability within the prefrontal cortex and sensory related cortex,resulting in diminished neural dynamic adaptability that compromises behavioral performance during visual-audio dual tasks.关键词
衰老/氧合血红蛋白/选择性注意/大脑信号变异性/功能性近红外光谱成像技术Key words
Aging/Oxyhemoglobins/selective attention/brain signal variability/functional near-infrared spectroscopy引用本文复制引用
寇诺男,王松建,刘怡,赵宵颖,刘潼,王媛,王硕..衰老对视听双任务大脑信号变异性的影响[J].中国耳鼻咽喉头颈外科,2025,32(2):76-81,6.基金项目
国家自然科学基金(82301300) （82301300）
首发重点公关课题(首发-2024-1-1091) （首发-2024-1-1091）
北京市自然科学基金(7252010) （7252010）
高层次公共卫生技术人才建设项目(学术骨干-02-42) （学术骨干-02-42）
首都卫生发展科研专项(首发2022-4-1093) （首发2022-4-1093）
