军事医学2025，Vol.49Issue(2)：110-113,4.DOI:10.7644/j.issn.1674-9960.2025.02.004
舒肝解郁胶囊对慢性心力衰竭伴焦虑抑郁患者心功能和心理状态的影响
Effects of Shugan Jieyu capsules on cardiac function and state of mind of chronic heart failure patients with anxiety and depression
摘要
Abstract
Objective To study the effects of Shugan Jieyu capsules on the cardiac function and state of mind of chronic heart failure(CHF)patients with anxiety and depression.Methods Ninety-four CHF patients with anxiety and depression were randomly divided into the Shugan Jieyu capsule treatment group and mental therapy control group.Self-rating depression Scale(SDS),self-rating anxiety scale(SAS),left ventricular ejection fraction(LVEF),N-terminal pro-B-type natriuretic peptide(NT-proBNP),the 6-minute walking test(6MWT),hemoglobin(Hb),interleukin-6(IL-6),albumin(ALB)and high-sensitivity c-reactive protein(hs-CRP)were compared between the two groups before and after treatment using t-tests and chi-square tests in order to find out about the efficacy of Shugan Jieyu capsules in CHF patients with anxiety and depression.Results After 8 weeks of treatment,SDS,SAS,NT-proBNP,hs-CRP and IL-6 were all significantly lower,especially in the treatment group,while LVEF,6MWT,Hb and ALB were significantly higher or longer,particularly in the treatment group.Conclusion Shugan Jieyu capsules can effectively alleviate anxiety and depression in CHF patients,improve the cardiac function and nutritional status,and mitigate inflammation.关键词
舒肝解郁胶囊/慢性心力衰竭/焦虑/抑郁/心功能Key words
Shugan Jieyu capsule/chronic heart failure/depression/anxiety/cardiac function分类
临床医学引用本文复制引用
王斌,逄帅,吕水利,常快乐..舒肝解郁胶囊对慢性心力衰竭伴焦虑抑郁患者心功能和心理状态的影响[J].军事医学,2025,49(2):110-113,4.基金项目
陕西省科学技术厅国际科技合作计划项目(2023-GHYB-12) （2023-GHYB-12）
