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Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair

Yuhao Jiang Chao Zhao Chenyang Zhang Weilin Li Di Liu Bailin Zhao

生物物理学报（英文）2025，Vol.11Issue(1)：46-55,10.

生物物理学报（英文）2025，Vol.11Issue(1)：46-55,10.DOI:10.52601/bpr.2024.240043

Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair

Yuhao Jiang ¹Chao Zhao ²Chenyang Zhang ³Weilin Li ³Di Liu ¹Bailin Zhao³

作者信息

1. Department of Hematology,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710004,China||Institute of Molecular and Translational Medicine(IMTM),and Department of Biochemistry and Molecular Biolo-gy,Xi'an Jiaotong University Health Science Center,Xi'an 710061,China
2. Institute of Biomedical and Health Engineering,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,Guangdong,China
3. Institute of Molecular and Translational Medicine(IMTM),and Department of Biochemistry and Molecular Biolo-gy,Xi'an Jiaotong University Health Science Center,Xi'an 710061,China
折叠

摘要

关键词

Single-molecule techniques/smFRET/Magnetic tweezers/Non-homologous end joining(NHEJ)/DNA Synapsis

Key words

Single-molecule techniques/smFRET/Magnetic tweezers/Non-homologous end joining(NHEJ)/DNA Synapsis

引用本文复制引用

Yuhao Jiang,Chao Zhao,Chenyang Zhang,Weilin Li,Di Liu,Bailin Zhao..Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair[J].生物物理学报（英文）,2025,11(1):46-55,10.

基金项目

The authors would like to thank the mem-bers of the Zhao laboratory for helpful discussions and com-ments on this review.We apologize that many research findings were not directly cited because of the space limitation.This work is supported by the National Natural Science Foundation of China(22104120),the Three Qin Talents Introduction Pro-gram for Youths of Shaanxi Province(2023SYJ26),the Funda-mental Research Funds for the Central Universities(xtr052023008),and the"Young Talent Support Plan"of Xi'an Jiaotong University to Bailin Zhao （22104120）

and by the National Natural Science Foundation of China(32400427),the China Postdoctor-al Science Foundation(2022M712546),the Fundamental Re-search Funds for the Central Universities(xzy012023018),and the Postdoctoral Research Project of Shaanxi Province(2023BSHEDZZ07)to Di Liu （32400427）

and by the Fundamental Research Funds for the Central Universities(xzy022024035)to Chenyang Zhang. （xzy022024035）

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