中国医疗设备2025，Vol.40Issue(4)：158-163,176,7.DOI:10.3969/j.issn.1674-1633.20240866
帕金森病伴快速眼动睡眠行为障碍的静息态功能磁共振研究进展
Research Progress in Resting-State Functional MRI of Parkinson's Disease with Rapid Eye Movement Sleep Disorder
摘要
Abstract
Parkinson's disease(PD)is a progressive neurodegenerative disorder mainly manifested by motor symptoms,and it can also be accompanied by various non-motor symptoms.Approximately 33%-46%of PD patients are comorbid with rapid eye movement sleep behavior disorder(RBD).RBD is one of the key prodromal symptoms of PD,and its early occurrence provides an opportunity for the early diagnosis and early treatment of PD.Compared with the research based on brain structure using conventional MRI sequences,resting-state functional MRI(rs-fMRI)explores the neuropathological mechanisms of patients with PD complicated by RBD(PD RBD)from the perspective of brain functional networks,and searches for imaging targets for its diagnosis and treatment.In this way,it can improve the quality of life of patients,delay the progression of the disease,and reduce treatment costs.This article summarized the application progress of various analysis methods of rs-fMRI in PD RBD,with the hope of providing a reference for the precise diagnosis and treatment of PD RBD and promoting the overall improvement of the diagnosis and treatment level of PD RBD.关键词
帕金森病/快速眼动睡眠行为障碍/静息态功能磁共振/功能连接/影像学靶点/精准诊疗Key words
Parkinson's disease(PD)/rapid eye movement sleep behavior disorder/resting-state functional MRI(rs-fMRI)/functional connectivity/imaging targets/precise diagnosis and treatment分类
医药卫生引用本文复制引用
杨媛,高平..帕金森病伴快速眼动睡眠行为障碍的静息态功能磁共振研究进展[J].中国医疗设备,2025,40(4):158-163,176,7.基金项目
湖北省科技计划项目重点研发专项(2023BCB140) （2023BCB140）
襄阳市第一人民医院科技创新项目(XYY2023SD16). （XYY2023SD16）
