中国美容医学2025，Vol.34Issue(4)：90-94,5.
英花枇杷颗粒联合面针疗法治疗寻常痤疮的疗效及对患者血清DHEA和IL-4水平的影响
Influence of Yinghua Pipa Granule Combined with Facial Acupuncture Therapy on Efficacy and Serum DHEA and IL-4 Levels in Patients with Acne Vulgaris
刘晓梅 1王梦 1赵礼东1
作者信息
- 1. 安徽省阜阳市太和县中医院(阜阳市第二中医院)皮肤科 安徽 阜阳 236600
- 折叠
摘要
Abstract
Objective To explore the influence of Yinghua Pipa granule combined with facial acupuncture on serum dehydroepiandrosterone(DHEA)and interleukin 4(IL-4)levels in patients with acne vulgaris.Methods 102 patients with acne vulgaris in department of dermatology of Taihe Hospital of Traditional Chinese Medicine were included in the study from May 2020 to April 2023.According to the order of treatment,they were divided into study group(n=51)and control group(n=51)by random number table method.The control group was treated with conventional western medicine,while the observation group was given Yinghua Pipa granule combined with facial acupuncture on the basis of the control group.Both groups were treated for 4 weeks.The efficacy,skin lesion degree[Global Acne Grading System(GAGS)],laboratory indicators(serum DHEA,IL-4),adverse reactions and prognosis[Acne Specific Quality of Life Scale(QoL-Acne)]were compared.Results The total effective rate of treatment in study group after 4 weeks of treatment was higher than that in control group(P＜0.05).The GAGS score and serum DHEA and IL-4 levels in study group were lower compared to control group(P＜0.05).During treatment,there were no obvious differences in the incidence rates of adverse reactions between groups(P＞0.05).The QoL-Acne scores in study group after 4 weeks of treatment and after 3 months of follow-up were higher compared to control group(P＜0.05).Conclusion Yinghua Pipa granule combined with facial acupuncture has a significant effect in the treatment of acne vulgaris.It can effectively reduce the levels of serum DHEA and IL-4,lower the skin lesions and improve the quality of life,and it does not significantly increase the risk of treatment.关键词
英花枇杷颗粒/面针/寻常痤疮/DHEA/IL-4/疗效/皮损Key words
Yinghua Pipa granule/facial acupuncture/acne vulgaris/DHEA/IL-4/efficacy/skin lesions分类
临床医学引用本文复制引用
刘晓梅,王梦,赵礼东..英花枇杷颗粒联合面针疗法治疗寻常痤疮的疗效及对患者血清DHEA和IL-4水平的影响[J].中国美容医学,2025,34(4):90-94,5.
