中风与神经疾病杂志2025，Vol.42Issue(3)：204-208,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0040
阻塞性睡眠呼吸暂停低通气综合征与脑白质病变的相关性研究
Association between obstructive sleep apnea hypopnea syndrome and cerebral white matter lesions
王源 1王丹 2贺嘉 1勾海燕 1陈岩 1石佳琦 1曲悠扬 1朱雨岚 1朱延梅1
作者信息
- 1. 哈尔滨医科大学附属第二医院,黑龙江 哈尔滨 150000
- 2. 齐齐哈尔医学院附属第三医院,黑龙江 齐齐哈尔 161000
- 折叠
摘要
Abstract
Objective To investigate the association between obstructive sleep apnea hypopnea syndrome(OSAHS)and white matter lesions(WMLs).Methods A total of 91 patients who attended Department of Neurology and Department of Epilepsy and Sleep Disorders in The Second Affiliated Hospital of Harbin Medical University from June 2019 to December 2020 and met the diagnostic criteria for WMLs were enrolled as WMLs group,and 61 patients without WMLs were enrolled as control group.All subjects underwent brain MRI and PSG examinations,and related data were col-lected,including demographic data,past history,personal history,laboratory examination,and imaging findings.Results The WMLs group had a prevalence rate of OSAHS of 92.3%and an AHI of(32.85±19.86)events/hour on PSG,which were significantly higher than those in the control group(P<0.05).The Spearman rank correlation analysis showed a strong positive correlation between WMLs severity and OSAHS severity(r=0.602 52,P<0.0001).Conclusion The WMLs group is more susceptible to OSAHS than the control group,and the severity of WMLs is posi-tively correlated with the severity of OSAHS.关键词
脑白质病变/阻塞性睡眠呼吸暂停低通气综合征/脑小血管疾病/腔隙性梗死/脑微出血Key words
White matter lesions/Obstructive sleep apnea hypopnea syndrome/Cerebral small vessel dis-ease/Lacunar infarct/Cerebral microbleeds分类
临床医学引用本文复制引用
王源,王丹,贺嘉,勾海燕,陈岩,石佳琦,曲悠扬,朱雨岚,朱延梅..阻塞性睡眠呼吸暂停低通气综合征与脑白质病变的相关性研究[J].中风与神经疾病杂志,2025,42(3):204-208,5.
