针刺研究2025，Vol.50Issue(4)：439-447,9.DOI:10.13702/j.1000-0607.20231134
针刺通过调控海马神经可塑性改善抑郁症的研究进展
Research progress of acupuncture in attenuating depression via regulating hippocampal neuroplasticity
摘要
Abstract
Acupuncture has a significant effect on depression.The paper reviews the mechanism of acupuncture in treatment of depression based on hippocampal neuroplasticity from the relevant articles published in recent years from 3 aspects,i.e.promoting neuronal regeneration,improving synaptic plasticity efficiency,and repairing astrocytes structure and function.Acupuncture can regulate neural plasticity at multiple levels.It can not only directly repair the structure of neurons and glial cells through acupoint stimulation,but also indirectly participate in the regulation of neural plasticity through monoamine neurotransmitters,glutamate receptors,and related protein-mediated signaling pathways.关键词
针刺/抑郁症/海马/神经元/突触/胶质细胞Key words
Acupuncture/Depression/Hippocampus/Neuron/Synapse/Glial cell引用本文复制引用
赵季宇,苑功名,李佩云,徐媛,郭永明,公一囡..针刺通过调控海马神经可塑性改善抑郁症的研究进展[J].针刺研究,2025,50(4):439-447,9.基金项目
国家自然科学基金项目(No.82205279、82274649、82004473) （No.82205279、82274649、82004473）
