摘要
Abstract
Objective To explore the aesthetic effect of 755 nm picosecond laser combined with Shumin Star on facial melasma and its influences on skin barrier function and scores of clinical symptoms.Methods A total of 120 patients with melasma confirmed in the hospital were enrolled between June 2019 and June 2023.According to random number table method,they were divided into combination group(n=60,755 nm picosecond laser combined with Shumin Star)and 755 nm group(n=60,755 nm picosecond laser).All patients were treated for 6 months.The cosmetic effect,skin barrier function,score of melasma area severity index(MASI)and the occurrence of adverse reactions were compared between the two groups.Results After 6 months of treatment,scores of MI and EI were decreased in both groups,which were lower in combination group than 755 nm group(P＜0.05).After 6 months of treatment,TEWL score in combination group was lower than that in 755 nm group,water and sebum content of cuticle were higher than those in 755 nm group(P＜0.05).After 2 month,4 months and 6 months of treatment,MASI scores in combination group were lower than those in 755 nm group(P＜0.05).After 6 months of treatment,there was no significant difference in the incidence of adverse reactions(swelling,bleeding,burning)between the two groups(P＞0.05).Conclusion 755 nm picosecond laser combined with Shumin Star can improve aesthetic effect,enhance barrier function and improve skin status in patients with facial melasma.关键词
755 nm皮秒激光/舒敏之星/黄褐斑/美学效果/屏障功能Key words
755 nm picosecond laser/Shumin Star/melasma/aesthetic effect/barrier function分类
医药卫生
