中国实用外科杂志2025，Vol.45Issue(3)：266-269,273,5.DOI:10.19538/j.cjps.issn1005-2208.2025.03.05
克罗恩病并发肠瘘综合治疗中的难点及对策
Difficulties and strategies in the comprehensive management of Crohn's disease complicated by intestinal fistulas
摘要
Abstract
Intestinal fistulas are a common complication of Crohn's disease(CD)and can lead to severe conditions such as intra-abdominal infections,sepsis,and necrotizing fasciitis,with a complex treatment process and a high mortality rate.CD-related intestinal fistulas are of various types and are typically classified into two major categories,enteroenteric and enterocutaneous fistulas,in clinical practice.In addition to the general pathophysiological characteristics of intestinal fistulas,CD-related fistulas are often associated with intestinal inflammation,malnutrition,and the side effects of therapeutic drugs,which complicate clinical management.With the development of novel drugs such as biologics and other advanced technologies,non-surgical treatment options for CD-related fistulas are emerging.However,surgical treatment remains the mainstay of therapy.A comprehensive treatment approach combining medical and surgical strategies,along with thorough disease assessment and prehabilitation,is essential to formulate the optimal treatment plan and maximize patient benefits.关键词
克罗恩病/肠瘘/生物制剂/手术治疗/炎症/营养不良/预康复/肠内营养Key words
Crohn's disease/intestinal fistula/biologics/sur-gical treatment/inflammation/malnutrition/perhabilitation/enteral nutrition分类
医药卫生引用本文复制引用
朱维铭,贡钰霞..克罗恩病并发肠瘘综合治疗中的难点及对策[J].中国实用外科杂志,2025,45(3):266-269,273,5.基金项目
National Natural Science Foundation of China(General Program,No.82170573) （General Program,No.82170573）
Jiangsu Provincial Traditional Chinese Medicine Science and Technology Development Plan Key Project(No.ZD202410) 国家自然科学基金面上项目(No.82170573) （No.ZD202410）
江苏省中医药科技发展计划重点项目(No.ZD202410) （No.ZD202410）
