癌症生物学与医学（英文版）2025，Vol.22Issue(3)：266-283,18.DOI:10.20892/j.issn.2095-3941.2024.0540
MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer
MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer
Ningxin Ren 1Yexiong Li 2Wen Tan 1Dongxin Lin 3Hongxia Chen 1Ying Huang 4Jing Jin 5Shaosen Zhang 1Ruoqing Yan 1Mengjie Li 1Linlin Zheng 1Shuangmei Zou6
作者信息
- 1. State Key Laboratory of Molecular Oncology,Department of Etiology and Carcinogenesis,Beijing Key Laboratory for Carcinogenesis and Cancer Prevention,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China
- 2. Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China
- 3. State Key Laboratory of Molecular Oncology,Department of Etiology and Carcinogenesis,Beijing Key Laboratory for Carcinogenesis and Cancer Prevention,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China||Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Guangzhou 510060,China
- 4. State Key Laboratory of Molecular Oncology,Department of Etiology and Carcinogenesis,Beijing Key Laboratory for Carcinogenesis and Cancer Prevention,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China||Department of Thoracic Surgery and Oncology,the First Affiliated Hospital of Guangzhou Medical University,State Key Laboratory of Respiratory Disease&National Clinical Research Center for Respiratory Disease,Guangzhou 510120,China
- 5. Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China||Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Shenzhen 518100,China
- 6. Department of Pathology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China
- 折叠
摘要
关键词
Colorectal cancer/chemoradiotherapy sensitivity/MDM1/YBX1/TP53Key words
Colorectal cancer/chemoradiotherapy sensitivity/MDM1/YBX1/TP53引用本文复制引用
Ningxin Ren,Yexiong Li,Wen Tan,Dongxin Lin,Hongxia Chen,Ying Huang,Jing Jin,Shaosen Zhang,Ruoqing Yan,Mengjie Li,Linlin Zheng,Shuangmei Zou..MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer[J].癌症生物学与医学（英文版）,2025,22(3):266-283,18.基金项目
This work was supported by grants from the National Natural Science Foundation(Grant No.81972859 to W.T.),Beijing Municipal Science&Technology Commission Grant(Grant No.D0905001040531 to D.L.),and State Key Laboratory of Molecular Oncology Grant(Grant No.SKLMO-KF2023-03 to D.L.). （Grant No.81972859 to W.T.）
