中国当代儿科杂志2025，Vol.27Issue(4)：389-394,6.DOI:10.7499/j.issn.1008-8830.2501080
输血依赖型地中海贫血患者生长障碍和内分泌功能的监测及干预
Monitoring and interventions of growth disorders and endocrine function in children with transfusion-dependent thalassemia
范歆 1黄逸云1
作者信息
- 1. 广西医科大学第二附属医院儿科,广西 南宁 530007
- 折叠
摘要
Abstract
Transfusion-dependent thalassemia(TDT)is a severe genetic chronic hemolytic disease,and growth retardation is a common clinical feature in patients with TDT.Due to the need for regular blood transfusions,these patients often experience iron overload,which leads to various endocrine dysfunctions,including abnormalities in the growth hormone/insulin-like growth factor axis,hypothyroidism,hypoparathyroidism,hypogonadism,adrenal insufficiency,and decreased bone density.This paper reviews the clinical monitoring and intervention measures for growth disorders and related endocrine functions in patients with TDT,providing references for clinicians.关键词
地中海贫血/内分泌功能障碍/生长发育/铁过载/重组人生长激素Key words
Thalassemia/Endocrine dysfunction/Growth and development/Iron overload/Recombinant human growth hormone引用本文复制引用
范歆,黄逸云..输血依赖型地中海贫血患者生长障碍和内分泌功能的监测及干预[J].中国当代儿科杂志,2025,27(4):389-394,6.
