中药材2024，Vol.47Issue(7)：1672-1677,6.DOI:10.13863/j.issn1001-4454.2024.07.013
基于正交试验和AHP-综合评分法优选醋红景天炮制工艺及质量控制研究
Optimization of Processing Technology and Quality Control of Rhodiolae Crenulatae Radix et Rhizoma Processing with Vinegar Based on Orthogonal Experiment and AHP-Comprehensive Scoring Method
摘要
Abstract
Objective:To optimize the processing technology of Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar and to control its quality.Methods:Orthogonal test was used to optimize the processing technology.The fingerprint of 15 batches of Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar was established by HPLC.Multivariate statistical analysis was carried out using cluster heat map,principal component analysis and good and bad solution distance method.Results:The best processing technology of Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar was stir-fried at 160℃for 16 min,with 15 kg rice vinegar for every 100 kg of materials.A total of 12 common peaks were identified in 15 batches of samples fingerprint,the similarity was equal or greater than 0.885.15 batches of samples could be clustered into four categories.TOPSIS analysis showed that the comprehensive quality of S12,S13 and S15 Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar was relatively good,while the comprehensive quality of S4,S9 and S14 was poor.Conclusion:The optimized Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar technology is stable and feasible,which provides a basis for practical production and application.关键词
醋红景天/正交试验/炮制工艺/指纹图谱/多元统计分析Key words
Rhodiolae Crenulatae Radix et Rhizoma processing with vinegar/Orthogonal test/Processing technology/Fingerprint/Multivariate statistical analysis分类
医药卫生引用本文复制引用
邓琦,罗红兵,钟凌云,刘斌,钟思敏,周颖,徐福余..基于正交试验和AHP-综合评分法优选醋红景天炮制工艺及质量控制研究[J].中药材,2024,47(7):1672-1677,6.基金项目
江西省中药标准化计划项目(2020B01,2020B04) （2020B01,2020B04）
中药炮制技术传承创新团队(CXTD22003) （CXTD22003）
建昌帮特色饮片炮制工艺及质量标准规范化研究(XMBH00031) （XMBH00031）
中药炮制(炆法)等关键技术重点研究室(赣中医药科教字[2022]8号) （炆法）
