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地锦全草化学成分研究

戴鹏宇 黄锦豪 张凯惠 刘方乐 王美琪 祝晨蔯 林朝展

中药材2024,Vol.47Issue(7):1688-1693,6.
中药材2024,Vol.47Issue(7):1688-1693,6.DOI:10.13863/j.issn1001-4454.2024.07.016

地锦全草化学成分研究

Chemical Constituents from the Whole Herb of Euphorbia humifusa

戴鹏宇 1黄锦豪 1张凯惠 1刘方乐 2王美琪 1祝晨蔯 1林朝展1

作者信息

  • 1. 广州中医药大学中药学院,广东 广州 510006
  • 2. 广州中医药大学第一附属医院,广东 广州 510405
  • 折叠

摘要

Abstract

Objective:To study the chemical constituents of Euphorbia humifusa whole herb.Methods:The methanol extract of Eu-phorbia humifusa whole herb was isolated and purified by column chromatography,and the structures of the compounds were identified by modern spectroscopy.Results:Twenty compounds were isolated from Euphorbia humifusa whole herb and identified as vitexin-2′-O-rhamnoside(1),ellagic acid-4′-O-(4″-O-galloyl)-xylopyranoside(2),hesperetin(3),isorhamnetin(4),quercitrin(5),naringin(6),naringenin(7),vitexin(8),isoquercitrin(9),quercetin-3-O-(2″-O-galloyl)-β-D-glucoside(10),quercetin-3-O-xylopyranosyl-(1→2)-β-D-glucoside(11),nicotiflorin(12),cosmosiin(13),3,3′-di-O-methylellagic acid(14),gallic acid(15),ethyl gallate(16),brevifolin(17),methyl brevifolincarboxylate(18),corilagin(19),syringin(20),respectively.Conclusion:Among them,compounds 1 to 3 are iso-lated from Euphorbia genus for the first time,compounds 4 to 7 are isolated from Euphorbia humifusa for the first time.

关键词

地锦草/化学成分/黄酮/酚酸

Key words

Euphorbia humifusa Willd./Chemical constituents/Flavonoids/Phenolic acids

分类

医药卫生

引用本文复制引用

戴鹏宇,黄锦豪,张凯惠,刘方乐,王美琪,祝晨蔯,林朝展..地锦全草化学成分研究[J].中药材,2024,47(7):1688-1693,6.

基金项目

国家自然科学基金项目(82174266,82374616) (82174266,82374616)

广东省自然科学基金项目(2023A1515011027) (2023A1515011027)

中药材

OA北大核心CSTPCD

1001-4454

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