中药材2024，Vol.47Issue(7)：1721-1727,7.DOI:10.13863/j.issn1001-4454.2024.07.021
指纹图谱结合多元化学计量法与熵权-TOPSIS的不同基原珍珠母药材质量评价
Quality Evaluation of Different Original Margaritifera Concha by Fingerprint Combined with Multivariate Chemometrics and Entropy Weight-TOPSIS Method
摘要
Abstract
Objective:To establish the fingerprint of different original Margaritifera Concha and determine the contents of multiple components,to evaluate the quality of different original Margaritifera Concha.Methods:According to the principle of amino acid precol-umn derivation of phenyl isothiocyanate(PITC),HPLC method was used to establish the fingerprint of Margaritifera Concha,and simi-larity evaluation and multivariate statistical analysis were carried out.The contents of 10 amino acids were determined and entropy weight-TOPSIS analysis was performed.Results:The similarity of fingerprint of 27 batches of Margaritifera Concha was above 0.900,13 common peaks were identified and 10 components were identified.Multivariate statistical analysis showed that alanine,glycine,L-lysine,valine and leucine were the key indexes that caused the quality difference of each original Margaritifera Concha.The entropy weight-TOPSIS results showed that the overall quality rankings of the different original Margaritifera Concha were Cristaria plicata,Pteria mar-tensii,Hyriopsis cumingii.Conclusion:This method established in the study can effectively analyze the quality of different original Marga-ritifera Concha,and provide a reference for comprehensive evaluation and control of Margaritifera Concha quality.关键词
珍珠母/指纹图谱/多元化学计量法/熵权-TOPSIS/质量评价Key words
Margaritifera Concha/Fingerprint/Multivariate chemometrics/Entropy weight-TOPSIS method/Quality evaluation分类
医药卫生引用本文复制引用
谈小飞,瞿彩丽,石炎林,吴回胜,胡辉,黄海华,汪文杰..指纹图谱结合多元化学计量法与熵权-TOPSIS的不同基原珍珠母药材质量评价[J].中药材,2024,47(7):1721-1727,7.基金项目
湖北省重点研发计划项目(2021ACA004,2022ACA003) （2021ACA004,2022ACA003）
湖北省光谷科创大走廊专项(2021BGE017) （2021BGE017）
