中山大学学报（医学科学版）2025，Vol.46Issue(2)：257-265,9.
环境污染物与儿童过敏性疾病相关性的研究进展
Research Progress on the Correlation Between Environmental Pollutants and Allergic Diseases in Children
摘要
Abstract
Allergic diseases pose an increasingly significant threat to children's health,with environmental pollutants playing a crucial role.Indoor and outdoor air pollution(such as particulate matter,nitrogen oxides,sulfur oxides,ozone,etc.),chemical contamination(such as persistent organic pollutants,heavy metals,etc.),and other environmental exposure factors(such as green spaces,viruses,meteorological conditions,diet,etc.)are all significant risk factors for allergic diseases in children.Particularly during the early life stages from the fetal period to infancy,exposure to environmental pollutants has a profound impact on the development of the immune system and the risk of future allergic diseases in children.It is worth noting that during these early life stages,certain specific dietary components(such as specific fatty acids,microorganisms,vitamins,etc.)and breastfeeding can provide some protection for children,reducing the incidence of allergic diseases.However,the mechanisms by which emerging persistent organic pollutants(such as chlorinated paraffins and perfluoroalkyl substances)interact with allergic diseases in children have not yet been fully elucidated.Additionally,the potential health impacts of green spaces and their components,as well as the relationship between household pet ownership and allergic diseases in children,remain key areas for future research.This article reviews the recent research progress on the correlation between environmental pollutants and allergic diseases in children,analyzes the mechanisms by which different environmental factors affect children's health,and aims to explore the impact of environmental pollutants on children's health in depth.It also provides a scientific basis for the prevention and treatment of allergic diseases in children.关键词
环境污染物/新污染物/过敏性疾病/儿童/环境暴露Key words
environmental pollutants/emerging pollutants/allergic diseases/children/environmental exposure分类
医药卫生引用本文复制引用
贺雨,刘爱平..环境污染物与儿童过敏性疾病相关性的研究进展[J].中山大学学报（医学科学版）,2025,46(2):257-265,9.基金项目
深圳市宝安区医疗卫生科研项目(2024JD278) （2024JD278）
