电化学（中英文）2025，Vol.31Issue(3)：25-34,10.DOI:10.61558/2993-074X.3516
金超微电极原位电沉积FeCo-MOF电化学检测肾上腺素
In-situ Electrodeposition of FeCo-MOF on Au Ultramicroelectrode for Highly Sensitive Detection of Epinephrine
摘要
Abstract
Metal-organic framework(MOF)nanostructures have emerged as a prominent class of materials in the advancement of electrochemical sensors.The rational design of bimetallic MOF-functionalized microelectrode is of importance for improv-ing the electrochemical performance but still in great challenge.In this work,the bimetallic FeCo-MOF nanostructures were assembled onto a gold disk ultramicroelectrode(Au UME,5.2 μm in diameter)via an in-situ electrodeposition method,which enhanced the sensitive detection of epinephrine(EP).The in-situ electrodeposited FeCo-MOF exhibited a character-istic nanoflower-like morphology and was uniformly dispersed on the Au UME.The FeCo-MOF/Au UME demonstrated excellent electrochemical performance on the detection of EP with a high sensitivity of 36.93 μA·μmol-1·L·cm-2 and a low detection limit of 1.28 μmol·L-1.It can be attributed to the nonlinear diffusion of EP onto the ultra-micro working substrate,coupled with synergistical catalytic activity of the bimetallic Fe,Co within MOF structure.Furthermore,the FeCo-MOF/Au UME has been successful applied to the analysis of EP in human serum samples,yielding high recovery rates.These results not only contribute to the expansion of the research area of electrochemical sensors,but also provide novel insights and directions into the development of high-performance MOF-based electrochemical sensors.关键词
FeCo-MOF/金超微电极/原位电沉积/电分析/肾上腺素Key words
FeCo-MOF/Gold disk ultramicroelectrode/In-situ electrodeposition/Electroanalysis/Epinephrine引用本文复制引用
陈妍,商建,万思宇,崔晓彤,刘中刚,郭正..金超微电极原位电沉积FeCo-MOF电化学检测肾上腺素[J].电化学（中英文）,2025,31(3):25-34,10.基金项目
We gratefully acknowledge the funding sup-port from the National Key Research and De-velopment Program of China(2021YFB3201400,2021YFB3201401,2020YFC1908602),the National Natural Science Foundation of China(21904001 and 61774159),the Anhui Provincial Natural Science Foundation(2008085QF288)and the Scientific Re-search Foundation for the Returned Overseas Chi-nese Scholars,Anhui Province(2020LCX032). （2021YFB3201400,2021YFB3201401,2020YFC1908602）
