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The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis

Zongchao Li Zhenhan Deng Liangjun Li Aonan Dai Xiaoxiang Fang Kexing Tang Kun Chen Peng Gao Jingyue Su Xin Chen Shengwu Yang

动物模型与实验医学（英文）2025，Vol.8Issue(4)：662-673,12.

动物模型与实验医学（英文）2025，Vol.8Issue(4)：662-673,12.DOI:10.1002/ame2.12529

The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis

Zongchao Li ¹Zhenhan Deng ²Liangjun Li ¹Aonan Dai ¹Xiaoxiang Fang ¹Kexing Tang ¹Kun Chen ¹Peng Gao ¹Jingyue Su ²Xin Chen ²Shengwu Yang²

作者信息

1. Department of Orthopaedics,The Affiliated Changsha Central Hospital,Hengyang Medical School,University of South China,Changsha,Hunan,China
2. Department of Orthopaedic Surgery,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China||Geriatrics Center,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China
折叠

摘要

关键词

chondrocyte/miR-6779/osteoarthritis/senescence/X-linked inhibitor of apoptosis protein

Key words

chondrocyte/miR-6779/osteoarthritis/senescence/X-linked inhibitor of apoptosis protein

引用本文复制引用

Zongchao Li,Zhenhan Deng,Liangjun Li,Aonan Dai,Xiaoxiang Fang,Kexing Tang,Kun Chen,Peng Gao,Jingyue Su,Xin Chen,Shengwu Yang..The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis[J].动物模型与实验医学（英文）,2025,8(4):662-673,12.

基金项目

The authors disclose receipt of the following financial or material support for the research,authorship,and/or publication of this article:National Natural Science Foundation of China(82472495),Natural Science Foundation of Hunan Province(2020JJ8043),Key Project of Hunan Provincial Health Commission(20201902 and C2019133),Natural Science Foundation of Changsha city,China(kq2403166),Hunan Provincial Clinical Medical Technology Innovation Guiding Project(2020SK53307),Basic Public Welfare Research projects of Wenzhou Science and Technology Bureau(Y20240087),and Start-up Funding for Talented Scientific Research of the First Affiliated Hospital of Wenzhou Medical University(2023QD026). （82472495）

动物模型与实验医学（英文）

ISSN：2096-5451

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