儿科药学杂志2025，Vol.31Issue(4)：25-29,5.DOI:10.13407/j.cnki.jpp.1672-108X.2025.04.006
临床药师参与1例反复发作性胆管炎患儿抗感染治疗的药学实践
Pharmaceutical Practice of Anti-Infective Treatment for a Child with Recurrent Cholangitis by Clinical Pharmacists
王东亮 1丁李乙 2尤一雯3
作者信息
- 1. 淮安市妇幼保健院,江苏淮安 223001
- 2. 中国医科大学,沈阳 110122
- 3. 淮安市第三人民医院,江苏淮安 223001
- 折叠
摘要
Abstract
Objective:To analyze the treatment process of a child with recurrent cholangitis(RC)after laparoscopic portojejunal anastomosis(Kasai portoenterostomy),and to provide reference for the treatment of RC.Methods:According to the biliary tract infection in children,laboratory tests,and literature evidence,clinical pharmacists assisted clinicians to optimize RC anti-infective regimen,and to deal with the secondary infection and bacterial resistance induced by long-term use of antibiotics,and to provide comprehensive pharmaceutical care for children.Meropenem combined with vancomycin and trimethoprim-sulfamethoxazole was recommended for the treatment of cholangitis complicated with bloodstream infection.Moreover,the deescalation therapy involving ciprofloxacin combined with metronidazole was suggested.Results:The clinicians accepted the clinical pharmacists'advice and used drugs such as compound trimethoprim-sulfamethoxazole and ciprofloxacin to control the cholangitis effectively.Conclusion:The long-term management of RC requires timely adjustment of the therapeutic strategy to effectively control the infection.关键词
胆道闭锁/胆管炎/临床药师/抗感染治疗/药学监护Key words
biliary atresia/recurrent cholangitis/cIinical pharmacists/anti-infective treatment/pharmaceutical care分类
药学引用本文复制引用
王东亮,丁李乙,尤一雯..临床药师参与1例反复发作性胆管炎患儿抗感染治疗的药学实践[J].儿科药学杂志,2025,31(4):25-29,5.
