康复学报2025，Vol.35Issue(2)：197-204,8.DOI:10.3724/SP.J.1329.2025.02013
外骨骼机器人对脑卒中患者平衡和下肢功能的影响Meta分析
Effects of Exoskeleton Robots on Balance and Lower Limb Function of Patients with Stroke:A Meta-Analysis
摘要
Abstract
Objective To evaluate the effects of exoskeleton robot training on balance and lower limb function of patients with stroke by meta-analysis.Methods Data were searched and retrieved from the database of China National Knowledge Infra-structure(CNKI),Wanfang Data,Chinese Science and Technology Periodical Database(VIP),PubMed,Cochrane Library,EMbase,and Web of Science.The randomized controlled trials(RCTs)of exoskeleton robots training on balance and lower limb function of patients with stroke were included,and the retrieval time was from the database inception to June 2024.The primary outcome indica-tors included Berg Balance Scale(BBS)score and Fugl-Meyer Assessment of Lower Extremity(FMA-UE)score.Data extraction and literature quality assessment were independently conducted by two researchers,and the meta-analysis was performed using Stata 16.0 software.Continuous variables were expressed by weighted mean difference(WMD)with 95%confidence interval(CI).The heterogeneity was determined according to the I 2 value.If I 2≤50%and P≥0.1,indicating low or no heterogeneity among the studies,a fixed-effect model would be used;if P<0.1,I 2>50%,indicating high heterogeneity,a random effect model would be used.Results A total of 9 RCTs were included,involving 467 patients.The meta-analysis results showed that,compared with the control group,BBS score in the experimental group after treatment was significantly higher[WMD=2.24,95%CI(0.57,3.91),Z=2.63,P=0.009]and FMA-LE score was significantly higher[WMD=2.30,95%CI=(1.39,3.21),Z=4.97,P<0.001].Subgroup meta-analysis of BBS scores showed that,when gait training lasted≤30 minutes,BBS score in the experimental group after treatment was signifi-cantly higher than the control group[WMD=2.49,95%CI(0.76,4.23),Z=2.82,P=0.005];when gait training duration was>30 min-utes,there was no statistically significant difference in BBS scores between two groups[WMD=-1.04,95%CI=(-7.23,5.15),Z=-0.33,P=0.743];when the intervention period was≤4 weeks,BBS score in the experimental group after treatment was significantly higher than the control group[WMD=1.86,95%CI=(0.10,3.62),Z=2.07,P=0.038];when the intervention period was>4 weeks,BBS score in the experimental group after treatment was significantly higher than the control group[WMD=5.57,95%CI=(0.31,10.82),Z=2.08,P=0.038].Subgroup analysis of FMA-LE scores showed that,when gait training duration was≤30 minutes,FMA-LE score in the experimental group after treatment was significantly higher than the control group[WMD=2.29,95%CI=(1.35,2.23),Z=4.78,P<0.001];when gait training duration was>30 minutes,there was no statistically significant difference in FMA-LE scores be-tween the two groups[WMD=2.45,95%CI=(-1.04,5.94),Z=1.38,P=0.169];when the intervention period was≤4 weeks,FMA-LE score in the experimental group after treatment was significantly higher than the control group[WMD=1.96,95%CI=(0.71,3.22),Z=2.43,P=0.002];when the intervention period was>4 weeks,FMA-LE score in the experimental group after treatment was signifi-cantly higher than the control group[WMD=2.66,95%CI=(1.35,3.97),Z=2.77,P<0.001].Conclusion Exoskeleton robot training can effectively improve balance and lower limb motor function of patients with stroke,and the improvement effect of short-term exo-skeleton robot training is more obvious.关键词
脑卒中/外骨骼机器人/平衡功能/下肢运动功能/Meta分析Key words
stroke/exoskeleton robots/balance function/lower limb function/meta-analysis引用本文复制引用
彭小柯,赵国顺,韩诗雨,董安琴..外骨骼机器人对脑卒中患者平衡和下肢功能的影响Meta分析[J].康复学报,2025,35(2):197-204,8.基金项目
国家重点研发计划项目(2022YFC3601700) （2022YFC3601700）
河南省高等学校重点科研项目(24A320018) （24A320018）
