首页|期刊导航|肝脏研究（英文）|Combination of brefeldin A and tunicamycin induces apoptosis in HepG2 cells through the endoplasmic reticulum stress-activated PERK-eIF2α-ATF4-CHOP signaling pathway

Combination of brefeldin A and tunicamycin induces apoptosis in HepG2 cells through the endoplasmic reticulum stress-activated PERK-eIF2α-ATF4-CHOP signaling pathway

Minghong Li Mengyi Duan Ying Yang Xingdao Li Dan Li Wenting Gao Xiaotong Ji Jianying Bai

肝脏研究（英文）2025，Vol.9Issue(1)：49-56,8.

肝脏研究（英文）2025，Vol.9Issue(1)：49-56,8.DOI:10.1016/j.livres.2025.01.004

Combination of brefeldin A and tunicamycin induces apoptosis in HepG2 cells through the endoplasmic reticulum stress-activated PERK-eIF2α-ATF4-CHOP signaling pathway

Minghong Li ¹Mengyi Duan ²Ying Yang ²Xingdao Li ²Dan Li ²Wenting Gao ²Xiaotong Ji ²Jianying Bai³

作者信息

1. Department of Environmental Health,School of Public Health,Shanxi Medical University,Taiyuan,Shanxi,China||Department of Occupational Disease Control,Ansteel Group General Hospital,Anshan,Liaoning,China
2. Department of Environmental Health,School of Public Health,Shanxi Medical University,Taiyuan,Shanxi,China
3. Department of Environmental Health,School of Public Health,Shanxi Medical University,Taiyuan,Shanxi,China||MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention,Taiyuan,Shanxi,China||Center for Ecological Public Health Security of Yellow River Basin,Shanxi Medical University,Taiyuan,Shanxi,China
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摘要

关键词

Brefeldin A(BFA)/Tunicamycin(TM)/Hepatocellular carcinoma(HCC)/Apoptosis/Endoplasmic reticulum stress(ERS)/Caspase-3

Key words

Brefeldin A(BFA)/Tunicamycin(TM)/Hepatocellular carcinoma(HCC)/Apoptosis/Endoplasmic reticulum stress(ERS)/Caspase-3

引用本文复制引用

Minghong Li,Mengyi Duan,Ying Yang,Xingdao Li,Dan Li,Wenting Gao,Xiaotong Ji,Jianying Bai..Combination of brefeldin A and tunicamycin induces apoptosis in HepG2 cells through the endoplasmic reticulum stress-activated PERK-eIF2α-ATF4-CHOP signaling pathway[J].肝脏研究（英文）,2025,9(1):49-56,8.

基金项目

This work was supported by the National Natural Science Foundation of China(No.30972445)and the Natural Science Foundation of Shanxi Province of China(No.202203021211231). （No.30972445）

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