耕作与栽培2025，Vol.45Issue(3)：22-28,7.
云南金花茶多酚微胶囊降血糖的潜在机制研究
Potential Mechanism of Hypoglycemic Effect of Microencapsulated Camellia fascicularis Polyphenols
摘要
Abstract
Camellia fascicularis is a very small population plant endemic in Yunnan.Its flowers are golden yellow in color and contain a variety of nutrients and health-care ingredients,especially phenol-ic substances.In order to investigate the potential mechanisms underlying the hgpoglycemic effects of Camellia fascicularis polyghenol microcapsules,pharmacological approaches were employed in this study.The results showed that a total of 31 metabolites identified in samples from the gastric diges-tion group(OG)and the intestinal digestion group(OGI)were initially screened through the TCMIP database to obtain 23 effective ingredients and 12 overlapping targets were selected.GO function and KEGG pathway enrichment analysis showed that phenolic substances exert hypoglycemic effects through multiple signal pathways.Molecular docking results showed that there was a good binding ac-tivity between the active ingredients produced during gastrointestinal digestion by zein-SA-CFP and T2 DM targets.关键词
云南金花茶/多酚/降血糖作用/分子对接Key words
Camellia fascicularis/polyphenol/hypoglycemic effect/molecular docking分类
农业科技引用本文复制引用
高妙姿,唐剑东,唐军荣,阚欢,张颖君,张贵良,赵平,刘云..云南金花茶多酚微胶囊降血糖的潜在机制研究[J].耕作与栽培,2025,45(3):22-28,7.基金项目
云南省教育厅科学研究基金项目(2022Y591) （2022Y591）
