实用心电与临床诊疗2025，Vol.34Issue(2)：176-180,187,6.DOI:10.13308/j.issn.2097-5716.2025.02.005
IL-6、NLR联合初始T1值在病毒性心肌炎患者预后评估中的价值
Value of interleukin-6,NLR combined with native T1 value in prognosis evaluation of patients with viral myocarditis
李艳红 1何骞2
作者信息
- 1. 411100 湖南湘潭,湘潭市中心医院检验科
- 2. 411100 湖南湘潭,湘潭市中心医院放射科
- 折叠
摘要
Abstract
Objective To explore interleukin-6(IL-6)and neutrophils to lymphocytes ratio(NLR)combined with native T1 value in the prognosis evaluation of patients with viral myocarditis(VMC).Methods A total of 156 patients with confirmed VMC were selected as research objects.After 12 months of follow-up,they were grouped into a poor prognosis group(40 cases)and a good prognosis group(116 cases)according to the follow-up results.The clinical data of the patients were collected,and Logistic regression analysis was used to investigate the influence of IL-6,NLR and native T1 value on the prognosis of VMC patients.ROC curve was utilized to evaluate the predictive efficiency of the above parameters for the prognosis of VMC patients.Results The levels of IL-6,hs-cTn I and NT-proBNP,NLR,and native T1 value in the poor prognosis group were all significantly higher than those in the good prognosis group,and the differences were all statistically significant(all P<0.05).Binary Logistic regression analysis showed that IL-6,NLR and native T1 value were all independent influencing factors for the prognosis of VMC.ROC analysis demonstrated that the effect of the combination of IL-6(regarding 12.895 pg/mL as the optimal cut-off value),NLR(regarding 3.495 as the optimal cut-off value)and native T1 value(regarding 1 122.0 ms as the optimal cut-off value)in predicting the prognosis of VMC patients was better than that of any single test,with a sensitivity of 87.5%and a specificity of 96.6%.Conclusion The level of IL-6,NLR and native T1 value were significantly elevated in VMC patients with poor prognosis,and they could be served as auxiliary predictive indicators for the prognosis.The combined detection of the three indicators shows good predictive efficiency for poor prognosis of VMC.关键词
病毒性心肌炎/预后评估/白细胞介素-6/中性粒细胞与淋巴细胞比值/初始T1值Key words
viral myocarditis/pognosis evaluation/interleukin-6/neutrophils to lymphocytes ratio/native T1 value分类
临床医学引用本文复制引用
李艳红,何骞..IL-6、NLR联合初始T1值在病毒性心肌炎患者预后评估中的价值[J].实用心电与临床诊疗,2025,34(2):176-180,187,6.
