实用心电与临床诊疗2025，Vol.34Issue(2)：194-198,5.DOI:10.13308/j.issn.2097-5716.2025.02.008
胎儿脐动脉血流参数对妊娠期高血压患者胎儿生长受限的预测价值
Predictive value of fetal umbilical artery blood flow parameters for fetal growth restriction in patients with gestational hypertension
摘要
Abstract
Objective To explore the predictive value of fetal umbilical artery blood flow parameters[pulsatility index(PI),resistance index(RI)and systolic peak/diastolic peak(S/D)]for fetal growth restriction(FGR)in patients with gestational hypertension,providing effective references for early clinical diagnosis.Methods A total of 85 patients with gestational hypertension were enrolled,and they were divided into a group with FGR(25 cases)and a group without FGR(60 cases)based on the presence or absence of FGR.The fetal umbilical artery blood flow parameters were compared between the two groups,and among patients with varying severities of illness.The correlation between these parameters and the severity of illness or FGR was analyzed by Spearman's method,while the predictive value of PI,RI and S/D for FGR was assessed by the ROC curve analysis.The early warning effect of different levels of fetal umbilical artery blood flow parameters on FGR was explored by relative risk(RR)analysis.Results The PI,RI,and S/D values in the group with FGR were all higher than those in the group without FGR,and the differences were statistically significant(all P<0.01).The PI,RI and S/D values among patients with varying severities of illness were ranked in order as:severe preeclampsia>mild preeclampsia>gestational hypertension,with statistically significant differences(all P<0.05).PI,RI,and S/D were all positively correlated with the severity of illness and FGR(all P<0.01).The AUC value of the combined prediction of fetal umbilical artery blood flow parameters for FGR was 0.885,with a Youden index of 0.770,the optimal prediction sensitivity of 92.00%,and a specificity of 85.00%.The RR of the occurrence of FGR in gestational hypertension patients with high levels of PI,RI,and S/D was 6.115 times,6.729 times,and 3.857 times of that in patients with low levels,respectively.And these parameters had significant early warning effect on the occurrence of FGR(all P<0.01).Conclusion The blood flow parameters of the fetal umbilical artery are closely related to the severity of disease and the occurrence of FGR among patients with gestational hypertension.The combined detection of each parameter has certain predictive value for the outcome of FGR in these patients.关键词
妊娠期高血压/胎儿生长受限/胎儿脐动脉血流/预测价值Key words
gestational hypertension/fetal growth restriction/fetal umbilical artery blood flow/predictive value分类
医药卫生引用本文复制引用
郭歌,张静敏,王迁..胎儿脐动脉血流参数对妊娠期高血压患者胎儿生长受限的预测价值[J].实用心电与临床诊疗,2025,34(2):194-198,5.基金项目
河南省医学科技攻关联合共建项目(LHGJ20213159) （LHGJ20213159）
