检验医学与临床2025，Vol.22Issue(8)：1019-1023,5.DOI:10.3969/j.issn.1672-9455.2025.08.003
半导体激光联合复方氯己定地塞米松膜对慢性牙周炎患者牙周指标及牙龈沟液炎症指标的影响
Effect of semiconductor laser combined with compound chlorhexidine and dexamethasone membrane on periodontal indexes and gingival crevicular fluid inflammation indexes in patients with chronic periodontitis
摘要
Abstract
Objective To investigate the effect of semiconductor laser combined with compound chlorhexi-dine and dexamethasone membrane on periodontal indexes and gingival sulcus inflammation indexes in pa-tients with periodontitis.Methods Ninety-two patients with chronic periodontitis admitted to the hospital from January 2023 to March 2024 were selected as the subjects.The patients were divided into the observation group and the control group according to random number table method,with 46 cases in each group.Both groups were treated with routine cleaning and subgingival scaling.The control group was treated with com-pound chlorhexidine and dexamethasone membrane on the basis of the treatment,and the observation group was treated with semiconductor laser on the basis of the control group.The clinical efficacy,periodontal inde-xes,gingival crevicular fluid inflammation indexes,masticatory function score,gingival microcirculation inde-xes and adverse reactions were compared between the two groups.Results The total effective rate of the ob-servation group was 93.48%,which was higher than 78.26%of the control group(P<0.05).After treat-ment,the plaque index,gingival index and periodontal pocket depth of the two groups were lower than those before treatment(P<0.05),and those of the observation group were lower than those of the control group(P<0.05).After treatment,the levels of interleukin(IL)-6,IL-8 and tumor necrosis factor(TNF)-α in gin-gival crevicular fluid of the two groups were lower than those before treatment(P<0.05),and those in the observation group were lower than those in the control group(P<0.05).After treatment,the masticatory function scores and gingival blood flow of the two groups were higher than those before treatment(P<0.05),and those of the observation group were higher than those of the control group(P<0.05).After treat-ment,the blood flow velocity of the two groups was faster than that before treatment(P<0.05),and the ob-servation group was faster than the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Semiconductor laser combined with compound chlorhexidine and dexamethasone membrane can effectively improve the efficacy of patients with chronic periodontitis,improve the periodontal index,gingival crevicular fluid inflammation index,masti-catory function and gingival microcirculation index,and does not increase the risk of adverse reactions.关键词
半导体激光/复方氯己定地塞米松膜/慢性牙周炎/牙周指标/炎症指标Key words
semiconductor laser/compound chlorhexidine and dexamethasone membrane/chronic pe-riodontitis/periodontal index/inflammation index分类
医药卫生引用本文复制引用
冯辉,黎佳灵,陈一,吕宗凯,罗智宇..半导体激光联合复方氯己定地塞米松膜对慢性牙周炎患者牙周指标及牙龈沟液炎症指标的影响[J].检验医学与临床,2025,22(8):1019-1023,5.基金项目
四川省医疗卫生与健康促进会2023年度科研项目(KY2023QN0239) （KY2023QN0239）
四川省科技厅2023年科技项目(2023JDR0209). （2023JDR0209）
