检验医学与临床2025，Vol.22Issue(8)：1096-1099,1105,5.DOI:10.3969/j.issn.1672-9455.2025.08.017
冠状动脉旁路移植术与经皮冠状动脉介入术治疗冠状动脉慢性完全闭塞病变的对比研究
A comparative study of coronary artery bypass grafting and percutaneous coronary intervention in the treatment of chronic total occlusion of coronary arteries
王锡峥 1杨毅 1齐弘炜 1赵建刚 1陈楠 1袁彪1
作者信息
- 1. 首都医科大学附属北京同仁医院心血管疾病诊疗中心心外科,北京 100176
- 折叠
摘要
Abstract
Objective To investigate the efficacy and safety of coronary artery bypass grafting(CABG)and percutaneous coronary intervention(PCI)in the treatment of patients with chronic total occlusion of coronary arteries(CTO),and to compare the differences in achieving complete revascularization,improving cardiac function and reducing the incidence of adverse events between these two treatment methods.Methods A total of 86 CTO patients admitted to the hospital from May 2019 to May 2023 were selected and divided into group A(n=43)and Group B(n=43)according to treatment methods.Group A was treated with CABG and group B with PCI.The complete revascularization[dynamic index(PI),vascular blood flow],hospitalization time,hospitalization cost,cardiac function indicators[left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),N-terminal brain natriuretic peptide(NT-proBNP)]1st day before and 7th day after surgery,and the incidence of adverse events during postoperative follow-up of the two groups were compared.Results The vascular blood flow and hospitaliza-tion cost in group A were higher than those in group B,and the hospitalization time in group A was longer than that in group B,and the differences were statistically significant(P<0.05).On the 7th day after opera-tion,LVEF in the two groups was higher than that on the 1st day before operation,LVEDD and LVESD were lower than those on the 1st day before operation,and NT-proBNP level was lower than that on the 1st day be-fore operation,and the differences were statistically significant(P<0.05).There were no significant differ-ences in LVEF,LVEDD,LVESD and NT-proBNP levels between the two groups 7th day after operation(P>0.05).There was no significant difference in the incidence of postoperative adverse events between the two groups(P>0.05).Conclusion CABG and PCI have similar effects and safety in the treatment of CTO,both of which can significantly improve patient cardiac function.CABG has advantages in achieving complete revas-cularization,while PCI helps to accelerate postoperative recovery and reduce economic burden.Both have pro-motional value in clinical applications.关键词
冠状动脉旁路移植术/经皮冠状动脉介入术/冠状动脉慢性完全闭塞病变/心功能指标Key words
coronary artery bypass grafting/percutaneous coronary intervention/chronic total occlu-sion of coronary artery/cardiac function indicator分类
临床医学引用本文复制引用
王锡峥,杨毅,齐弘炜,赵建刚,陈楠,袁彪..冠状动脉旁路移植术与经皮冠状动脉介入术治疗冠状动脉慢性完全闭塞病变的对比研究[J].检验医学与临床,2025,22(8):1096-1099,1105,5.
