临床神经病学杂志2025，Vol.38Issue(2)：81-86,6.
生物制剂治疗神经白塞综合征疗效的Meta分析
Meta-analysis of the effectiveness of biologics in the treatment of neuro-behçet's syndrome
李海素 1李海杰 2秦鹏3
作者信息
- 1. 250013 济南,山东第一医科大学附属中心医院消化内科
- 2. 山东第一医科大学第一附属医院肿瘤内科
- 3. 济南市第五人民医院神经内科
- 折叠
摘要
Abstract
Objective To observe the effectiveness of biological agents for the treatment of neuro-behçet's syndrome(NBS).Methods Databases including PubMed,Cochrane Library,Embase,Web of Science,CNKI,Wanfang,VIP,and CBM were searched for studies on biological agents for NBS.Meta-analysis was performed by Stata 16.0.Results Nine studies,comprising 140 NBS patients were included.Effect-size analysis showed that 92％of the treated patients in the analysis were responders to biological agents(95％CI:0.76-1.08).There was no significant inter-study heterogeneity(I2=0％).Conclusion Biological agents are effective treatments for NBS,especially in refractory cases,but more large-scale,high-quality controlled studies are needed to accurately assess the efficacy and safety of biologics in NBS patients.关键词
神经白塞综合征/生物制剂/疗效/Meta分析Key words
neuro-behçet's syndrome/biological agents/effectiveness/Meta analysis分类
临床医学引用本文复制引用
李海素,李海杰,秦鹏..生物制剂治疗神经白塞综合征疗效的Meta分析[J].临床神经病学杂志,2025,38(2):81-86,6.
