临床神经病学杂志2025，Vol.38Issue(2)：87-91,5.
以双侧尾状核病变为表现的髓鞘少突胶质细胞糖蛋白抗体相关性脑炎的临床及影像学特点(附1例报告)
Clinical and imaging features of myelin oligodendrocyte glycoprotein antibody associated encephalitis characterized by bilateral caudate nucleus lesions(report of one case)
丁俭 1金菁 1练学淦 1张超 2杨松1
作者信息
- 1. 213003 常州,苏州大学附属第三医院(常州市第一人民医院)神经内科
- 2. 天津医科大学总医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the clinical and imaging features of myelin oligodendrocyte glycoprotein(MOG)antibody associated encephalitis.Methods A case of MOG antibody associated encephalitis with bilateral caudate nucleus lesions as imaging manifestations was reported.Clinical data were summarised,diagnostic,differential diagnosis and therapeutic analyses were performed,and a review of relevant literature was conducted.Results The patient was a 31-year-old male with acute onset of illness,mainly presenting with headache,fever,increased CSF cells and proteins,serum anti-MOG antibody IgG positivity(1∶100),CSF anti-MOG antibody IgG positivity(1∶10),and abnormal signals of bilateral caudate nucleus head on cranial MRI.After hormonal shock treatment,the headache was relieved rapidly and the body temperature returned to normal.However,the CSF protein and serum MOG antibody titre were higher than before,and tolizumab was given.Conclusion MOG antibody-associated encephalitis has a variety of clinical and imaging manifestations,and this case is instructive for enriching its clinical features,imaging spectrum and exploring its treatment.关键词
髓鞘少突胶质细胞糖蛋白抗体相关性脑炎/影像学特点/预后Key words
myelin oligodendrocyte glycoprotein antibody associated encephalitis/imaging features/prognosis分类
临床医学引用本文复制引用
丁俭,金菁,练学淦,张超,杨松..以双侧尾状核病变为表现的髓鞘少突胶质细胞糖蛋白抗体相关性脑炎的临床及影像学特点(附1例报告)[J].临床神经病学杂志,2025,38(2):87-91,5.
