临床小儿外科杂志2025，Vol.24Issue(3)：292-295,4.DOI:10.3760/cma.j.cn101785-202111013-017
Klippel-Trenaunay综合征的研究进展
Research advances in Klippel-Trenaunay syndrome in children
摘要
Abstract
Klippel Trenaunay syndrome(KTS)is an overgrowth syndrome characterized by capillary malformations,venous malformations,extremity hypertrophy and with or without lymphatic malformations.It fre-quently occurs in neonates,infants and toddlers.Its etiology and pathogenesis have been associated with muta-tions in somatic PIK3CA gene.Its clinical manifestations are diverse and affect different organ systems.Current-ly there is no cure and conservative measures are applied.The major goals are early diagnosis,early interven-tion,reducing complications,promoting healthy development and improving quality-of-life.关键词
Klippel-Trenaunay综合征/静脉畸形/管理/淋巴管畸形/PIK3CA基因Key words
Klippel-Trenaunay Syndrome/Venous Malformations/Management/Lymphatic Malforma-tions/PIK3CA Gene引用本文复制引用
刘纪兰,刘海燕..Klippel-Trenaunay综合征的研究进展[J].临床小儿外科杂志,2025,24(3):292-295,4.基金项目
山东省自然科学基金面上项目(ZR2020MH144) General Project of Shandong Provincial Natural Science Foundation(ZR2020MH144) （ZR2020MH144）
