日用化学工业（中英文）2025，Vol.55Issue(4)：531-538,8.DOI:10.3969/j.issn.2097-2806.2025.04.016
UPLC-MS/MS法测定美白化妆品中10种植物原料指标性成分
Determination of 10 indicative components from plant materials in whitening cosmetics by UPLC-MS/MS
黄炜东1
作者信息
- 1. 泉州市食品药品检验所,福建 泉州 362000
- 折叠
摘要
Abstract
A method for simultaneous determination of 10 indicative components from plant materials in whitening cosmetics by ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)was established.The sample was extracted by ultrasonic extraction using 80%methanol,then separated on a Phenomenex Kinetex F5 column(3.0 mm×100 mm,2.6 μm)by gradient elution using 0.1%formic acid solution and acetonitrile as the mobile phases.The mass spectrometry was detected using electrospray ionization source(ESI),positive and negative ion simultaneous scanning and multiple reaction monitoring(MRM)mode.The results show that there are good linear relationships for 10 indicative components in their respective mass concentration rangers with the correlation coefficients(r)larger than 0.99.The limits of detection(LOD)are in the ranges of 0.07-1.93 μg/kg and the limits of quantitation(LOQ)are in the ranges of 0.22-6.42 μg/kg.The recoveries of toner,cream,emulsion and mask samples at three spiked levels for 10 indicative components are 80.5%-122.5%,with the relative standard deviations(RSD)of 1.3%-10.1%(n=6).With the advantages of accuracy,high sensitivity and simplicity,this method is suitable for qualitative identification and quantitative analysis of various indicative components from plant materials in various matrix types of whitening cosmetics.关键词
超高效液相色谱-串联质谱/美白化妆品/植物原料/指标性成分Key words
UPLC-MS/MS/whitening cosmetics/plant materials/indicative components分类
化学工程引用本文复制引用
黄炜东..UPLC-MS/MS法测定美白化妆品中10种植物原料指标性成分[J].日用化学工业（中英文）,2025,55(4):531-538,8.
