上海预防医学2025，Vol.37Issue(2)：125-128,4.DOI:10.19428/j.cnki.sjpm.2025.24323
2023年上海市黄浦区新发现人类免疫缺陷病毒感染者CD4+T淋巴细胞和病毒载量相关性
Correlation between CD4+T lymphocytes and viral load in newly identified human immunodeficiency virus infected individuals in Huangpu District,Shanghai,2023
摘要
Abstract
[Objective]To analyze the detected results of CD4+T lymphocytes and viral load in newly identified human immunodeficiency virus(HIV)infected patients in Huangpu District of Shanghai in 2023,to explore the correlation between them,so as to provide a scientific basis for the development of targeted prevention and control measures and antiviral treatment programs.[Methods]The data of CD4 cell count,viral load and demographic characteristics of the newly infected patients living with HIV in Huangpu District,Shanghai in 2023 were collected and analyzed by using descriptive epidemiological method.[Results]The mean CD4 cell count of the 67 newly identified HIV infected patients in Huangpu District was(301.22±235.19)cells·µL-1,with a mean viral load of(5.15±1.28)×105 copies·mL-1.There were statistically significant differences in CD4 cell count and viral load among different age groups(P<0.05),but there were no statistically significant differences by gender and marital status(both P>0.05).The CD4 cell count and CD4/CD8 ratio both were negatively correlated with the lg value of viral load(r=-0.290,-0.378;P=0.027,0.002).[Conclusion]The CD4 cell counts of the newly identified HIV infected patients in Huangpu District in 2023 were generally low,the proportion of patients with high viral load was high,but the risk for elderly infected with HIV was high.The elderly have gradually become the key population for AIDS prevention and control in Huangpu District.It is recommended to expand HIV screening in the elderly to reduce the risk of HIV transmission and increase the rate of early detection and treatment.关键词
人类免疫缺陷病毒/CD4+T淋巴细胞/病毒载量/感染/老年人Key words
human immunodeficiency virus,HIV/CD4+T lymphocyte/virus load/infection/elderly分类
医药卫生引用本文复制引用
朱双,詹洁琼,宋黎黎,王宇,褚维,陈玮华,徐慧敏..2023年上海市黄浦区新发现人类免疫缺陷病毒感染者CD4+T淋巴细胞和病毒载量相关性[J].上海预防医学,2025,37(2):125-128,4.基金项目
上海市公共卫生体系建设三年行动计划(GWVI-3) （GWVI-3）
上海市黄浦区卫生健康系统科研项目(HLM202329) （HLM202329）
上海市黄浦区医学优势专科(2023PYZK04) （2023PYZK04）
