摘要
Abstract
Objective To observe the effect of Danshen injection combined with rhBNP on hemorheology and cardiac function in patients with acute attack of heart failure.Methods From January 2021 to September 2023,a total of 60 patients diagnosed with acute exacerbation of heart failure at Longnan Second People's Hospital were enrolled in this study.The patients were randomly assigned to either a control group or an observation group(30 patients each)using a random number table.The control group received recombinant human B-type natriuretic peptide(rhBNP)therapy,while the observation group was treated with Danshen injection in addition to rhBNP.Clinical efficacy,cardiac function parameters,hemodynamic indices,and the incidence of adverse reactions were compared between the two groups.Results The total treatment efficacy rate in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the observation group demonstrated a higher LVEF and lower LVESV and LVEDV than the control group(P<0.05).Additionally,PV,FIB,and HBV levels were significantly reduced in both groups,with the observation group showing lower values than the control group(P<0.05).The incidence of adverse reactions was 10.00%in the observation group and 6.67%in the control group,with no statistically significant difference(P>0.05).Conclusion The combination of Danshen injection and rhBNP demonstrates superior efficacy in treating acute heart failure exacerbations,improving cardiac function and hemodynamics without significantly increasing adverse reactions.关键词
丹参注射液/新活素/心衰/急性发作期/血液流变学/心功能Key words
Danshen injection/rhBNP/Heart failure/Acute attack/Hemorheology/Cardiac function分类
医药卫生
