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产前胎儿畸形筛查中应用二维超声联合四维超声的临床价值分析

侯晓艳 张兆欢

临床研究2025,Vol.33Issue(4):137-140,4.
临床研究2025,Vol.33Issue(4):137-140,4.DOI:10.12385/j.issn.2096-1278(2025)04-0137-04

产前胎儿畸形筛查中应用二维超声联合四维超声的临床价值分析

Clinical Value Analysis of Using Two-Dimensional Ultrasound Combined with Four-Dimensional Ultrasound in Prenatal Screening for Fetal Malformations

侯晓艳 1张兆欢1

作者信息

  • 1. 洛阳市妇幼保健院 超声医学科,河南 洛阳 471000
  • 折叠

摘要

Abstract

Objective To explore the diagnostic value of two-dimensional ultrasound combined with four-dimensional ultrasound in identifying fetal malformations.Methods A retrospective analysis was conducted on 100 pregnant women admitted to Luoyang Maternal and Child Health Hospital from June 2023 to August 2024,all of whom underwent both two-dimensional and four-dimensional ultrasound examinations.The detection rates of malformed fetuses were recorded,and the diagnostic results of two-dimensional ultrasound alone and in combination with four-dimensional ultrasound for fetal malformations were compared,using the outcomes of induction or delivery as the gold standard to analyze the diagnostic efficacy of the combined ultrasound methods.Results The outcomes of induction or delivery revealed a total of 21 cases of fetal malformations(21.00%).Among these,4 cases involved facial malformations(4.00%),4 cases involved central nervous system malformations(4.00%),4 cases involved circulatory system malformations(4.00%),and 4 cases involved skeletal malformations of the limbs(4.00%),with 5 cases classified as other malformations(5.00%).The Kappa value of two-dimensional ultrasound,four-dimensional ultrasound and two-dimensional ultrasound combined with four-dimensional ultrasound in detecting all kinds of fetal malformations is 0.564,which indicates that the consistency is acceptable.The sensitivity of two-dimensional ultrasound in diagnosing fetal malformations was 47.62%,the specificity was 97.47%,and the accuracy was 87.00%;for four-dimensional ultrasound,these values were 76.19%sensitivity,98.73%specificity,and 94.00%accuracy;while the combined examination yielded a sensitivity of 90.48%,specificity of 98.73%,and an accuracy of 97.00%.The sensitivity and accuracy of the combined examination for diagnosing fetal malformations were significantly higher than those of two-dimensional ultrasound alone(P<0.05).Conclusion The combination of two-dimensional and four-dimensional ultrasound demonstrates high sensitivity and accuracy in diagnosing various types of fetal malformations,providing valuable reference for clinical screening.

关键词

二维超声/四维超声/胎儿畸形/产前筛查

Key words

Two-dimensional ultrasound/four-dimensional ultrasound/fetal malformation/prenatal screening

分类

医药卫生

引用本文复制引用

侯晓艳,张兆欢..产前胎儿畸形筛查中应用二维超声联合四维超声的临床价值分析[J].临床研究,2025,33(4):137-140,4.

临床研究

2096-1278

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