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脊髓损伤患者康复期尿路感染特点及相关因素分析

张佳熠 李诗欣 骆沁熹 杨永红

中国康复2025,Vol.40Issue(4):217-222,6.
中国康复2025,Vol.40Issue(4):217-222,6.DOI:10.3870/zgkf.2025.04.005

脊髓损伤患者康复期尿路感染特点及相关因素分析

Characteristics and related factors of urinary tract infections during the rehabilitation phase in patients with spinal cord injury

张佳熠 1李诗欣 1骆沁熹 1杨永红2

作者信息

  • 1. 四川大学华西医院康复医学中心,成都 610041
  • 2. 四川大学华西医院康复医学中心,成都 610041||康复医学四川省重点实验室,成都 610041
  • 折叠

摘要

Abstract

Objective:To investigate the characteristics and risk factors associated with urinary tract infections(UTI)during the rehabilitation phase in patients with spinal cord injury(SCI).Methods:A retrospective analysis was conducted on electronic medical records of 2101 SCI patients treated in our rehabilitation department from 2013 to 2023.Demographic information,clinical features,and laboratory indicators were collected through the electronic medical record system.Patients were categorized into a non-infection group,an asymptomatic bacteriuria(ASB)group,and a symptomatic UTI group based on their UTI status.Multinomial logistic regression was used to analyze risk factors associated with UTI.Results:The incidence of UTI in SCI patients was 74.0%,41.8%in ASB group and 32.9%in symptomatic UTI group.Laboratory analysis indicated that inflammatory markers were significantly higher in symptomatic UTI patients than in the no-infection and ASB groups.Multinomial logistic regression re-vealed that female gender(ASB:OR=2.66;symptomatic UTI:OR=1.96)and neurogenic bladder(ASB:OR=1.97;symptomatic UTI:OR=3.94)were shared risk factors for both ASB and symptomatic UTI.Indwelling cath-eterization(OR=2.17),renal impairment(OR=1.35),and anticholinergic drug use(OR=1.39)were significant-ly associated with symptomatic UTI.Lower injury levels and coexisting pulmonary infections appeared protective a-gainst UTI,with D-level injury(OR=0.54)and pulmonary infections(OR=0.58)significantly reducing ASB risk,and C-level(OR=0.57),D-level(OR=0.28),and E-level(OR=0.47)injuries significantly lowering the risk of symptomatic UTI.Conclusion:The incidence of UTI is high among SCI patients during the rehabilitation phase,with distinct clinical features and risk factors for ASB and symptomatic UTI.Differentiated prevention and treatment strategies should be implemented based on the type of UTI,with enhanced monitoring and intervention for high-risk patients to improve quality of life.

关键词

脊髓损伤/尿路感染/无症状性菌尿/症状性尿路感染/危险因素/康复期

Key words

spinal cord injury/urinary tract infec-tion/asymptomatic bacteriuria/symptomatic urinary tract infection/risk factors/rehabilitation phase

分类

临床医学

引用本文复制引用

张佳熠,李诗欣,骆沁熹,杨永红..脊髓损伤患者康复期尿路感染特点及相关因素分析[J].中国康复,2025,40(4):217-222,6.

基金项目

四川省科技计划项目(2024NSFSC0539) (2024NSFSC0539)

中国康复

1001-2001

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