中国康复理论与实践2025，Vol.31Issue(4)：441-447,7.DOI:10.3969/j.issn.1006-9771.2025.04.009
基于心肺运动试验的脑卒中偏瘫患者心肺适能的特征
Characteristics of cardiorespiratory fitness in patients with post-stroke hemiplegia based on cardiopulmonary ex-ercise testing
摘要
Abstract
Objective To analyze the characteristics in heart,lung and skeletal muscles of patients with post-stroke hemiplegia,and explore the main contributors to the cardiorespiratory fitness(CRF)after stroke with cardiopulmonary exercise testing(CPET). Methods From December,2021 to July,2023,79 eligible stroke patients with hemiplegia were recruited from Shanghai Jing'an District Central Hospital;meanwhile,twelve age-and gender-matched healthy subjects were recruited as controls.All the subjects received CPET.Paired-samples t test or Wilcoxon signed rank test was used to compare the differences of the CPET derived parameters between twelve stroke patients and healthy subjects.Multiple lin-ear regression was used to analyze the main contributors to the CRF of stroke patients with hemiplegia. Results The peak oxygen uptake(VO2peak),anaerobic threshold(AT)/VO2peak%pred(∣t∣>7.027,P<0.001),and O2 pulse peak(Z=-2.433,P<0.05)were lower,and the volume of dead space(VD)/tidal volume(VTpeak)was higher in the patients than in the controls(t=4.217,P<0.01).Multiple linear regression analysis indicated that O2 pulse peak(B=0.461)and AT/VO2peak%pred(B=19.340)were the main contributors to the VO2peak of stroke patients with hemiplegia(P<0.01)after the removal of the interference of age,and AT/VO2peak%pred was the largest contributor. Conclusion The CRF of hemiplegic patients after stroke has decreased,especially for the output volume,the efficiency of gas exchange and aerobic capacity of skeletal muscles.Skeletal muscle aerobic capacity and cardiac blood-pumping function are the main contributors to the CRF,especially the aerobic capacity of skeletal muscles.关键词
脑卒中/心肺适能/心肺运动试验/运动耐量Key words
stroke/cardiorespiratory fitness/cardiopulmonary exercise test/exercise tolerance分类
临床医学引用本文复制引用
陈蒙晔,曲庆明,朱杰,陈祥贵,贾杰..基于心肺运动试验的脑卒中偏瘫患者心肺适能的特征[J].中国康复理论与实践,2025,31(4):441-447,7.基金项目
国家重点研发计划项目(No.2018YFC2002300) Supported by National Key Research and Development Program of China(No.2018YFC2002300) （No.2018YFC2002300）
