中国康复理论与实践2025，Vol.31Issue(4)：448-457,10.DOI:10.3969/j.issn.1006-9771.2025.04.010
静息态脑电图在脑卒中患者上肢运动功能评估中的应用
Application of resting-state electroencephalography in assessment of upper limb motor function of stroke patients
摘要
Abstract
Objective To investigate the features of resting-state electroencephalography(EEG)in stroke patients with limited upper limb movement,and assess its potential utility in evaluating upper limb motor function. Methods From March to August,2024,a total of 71 stroke patients with limited upper limb movement were enrolled as stroke group at the Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine;while 63 healthy participants matched for age and sex were recruited as control group.They were tested with 19-chan-nel resting-state EEG(rsEEG),calculating of the pairwise derived brain symmetry index(pdBSI)and Delta/Al-pha ratio(DAR).The motor function was assessed with Fugl-Meyer Assessment-Upper Extremities(FMA-UE),the upper limb recovery was evaluated with Brunnstrom Stages and the activities of daily living was assessed with modified Barthel index(MBI)in stroke patients, Results Compared with the control group,the pdBSI of Global lead,Frontal region,Central region and Posterior region across Delta,Alpha and Beta1 frequency bands were significantly higher in the stroke group than in the control group(|Z|>2.289,P<0.05);as well as the pdBSI of Global lead,Central region and Posterior region across The-ta bands(|Z|>3.016,P<0.01),the pdBSI of Global lead,Frontal region,Central region and Posterior region across Beta2 bands(|Z|>3.222,P<0.01),DAR of Global lead,Frontal region,Central region and Posterior re-gion(|Z|>6.565,P<0.001).In the stroke group,the pdBSI of Global lead(r=-0.280,P=0.018)and Central region(r=-0.304,P=0.010)across the Delta band were significantly negatively correlated with FMA-UE,as well as the pdBSI of Global leads(r=-0.289,P=0.014),Central region(r=-0.244,P=0.040)and Posterior region(r=-0.356,P=0.002)across the Beta1 band,and the DAR of Global lead(r=-0.431,P<0.001),Fron-tal region(r=-0.429,P<0.001),Central region(r=-0.491,P<0.001)and Posterior region(r=-0.482,P<0.001). Conclusion Asymmetry in spectral power between hemispheres in the Delta(0.5 to 4 Hz)and Beta(13 to 20 Hz)bands is found in stroke patients,especially in the central region,which correlates with upper limb function limitations.pdBSI Delta,pdBSI Beta1 and DAR are potential neuroelectrophysiological markers for assessing upper limb motor function in stroke patients.关键词
脑卒中/脑电图/上肢/运动功能Key words
stroke/electroencephalogram/upper extremety/motor function分类
临床医学引用本文复制引用
李鑫磊,魏伟,宋健,赵雨晴,孔维橙,蔡嘉玉,施浩然,薛偕华..静息态脑电图在脑卒中患者上肢运动功能评估中的应用[J].中国康复理论与实践,2025,31(4):448-457,10.基金项目
1.福建省认知功能康复重点实验室开放项目(No.XKF2023007) （No.XKF2023007）
2.福建中医药大学康复技术省部共建协同创新中心项目(No.X2022005) （No.X2022005）
3.福建省卫生健康科研项目医学创新课题(No.2024CXA048) Suppoerd by Open Research Project of Fujian Key Laboratory of Cognitive Function Rehabilitation(No.XKF2023007),Rehabilitation Technology Innovation Center by Joint Collaboration of Ministry of Education and Fujian Province,Fujian University of Traditional Chinese Medicine(No.X2022005),and Medical Innovation Project of Fujian Health Research Project(No.2024CXA048) （No.2024CXA048）
