中国康复理论与实践2025，Vol.31Issue(4)：476-483,8.DOI:10.3969/j.issn.1006-9771.2025.04.013
超声引导下骶管注射神经妥乐平和综合康复治疗重度骶丛神经损伤后遗症期的个案报道
Ultrasound-guided sacral canal injection of Neurotropin and comprehensive rehabilitation for the aftermath of se-vere sacral plexus injury:a case report
摘要
Abstract
Objective To observe the effect of ultrasound-guided sacral canal injection of Neurotropin combined with comprehen-sive rehabilitation on severe sacral plexus injury after sacral fracture. Methods A case with severe sacral plexus injury ten months after sacral fracture was reviewed.He accepted ultrasound-guided sacral canal injection of Neurotropin along with comprehensive rehabilitation,and was assessed with American Spinal Injury Association Impairment Scale(AIS)impairment scale,manual muscle testing,Visual An-alog Scale(VAS),modified Barthel Index(MBI),Short-form of Health Survey(SF-36)and Functional Gait As-sessment(FGA),and measured the nerve conduction velocity and the structural organization of the sacrococcy-geal ligament using nerve conduction velocity tests,electromyography(EMG)and ultrasound examination be-fore and after treatment. Results After four weeks and ten weeks of treatment,the muscle strength,and scores of MBI,FGA and SF-36 increased,while the ASIA score improved from grade D to grade E,and VAS score decreased.During follow-up,the VAS score and physical pain and general health status scores of the SF-36 increased.After ten weeks of treatment,nerve conduction velocity increased,latency shortened,and the amplitude of evoked action potentials increased.The presence of spontaneous sharp waves decreased,and the peak of active potentials increased.The peak of ac-tive potentials in the right gluteus maximus,vastus lateralis and gastrocnemius muscles increased.The structural organization of the sacrococcygeal ligament appeared clearer and more orderly.No adverse reaction was ob-served. Conclusion Ultrasound-guided sacral canal injection of Neurotropin combined with comprehensive rehabilitation is ef-fective on pain,activities of daily living and quality of life for patients with severe sacral plexus injury during the sequelae period.关键词
骶丛神经损伤/超声引导下骶管注射/神经妥乐平/康复Key words
sacral plexus injury/ultrasound-guided sacral canal injection/Neurotropin/rehabilitation分类
医药卫生引用本文复制引用
朱海丰,钱桂凤,丹禹钦,高静纯,唐婷婷,霍明,谢韶东..超声引导下骶管注射神经妥乐平和综合康复治疗重度骶丛神经损伤后遗症期的个案报道[J].中国康复理论与实践,2025,31(4):476-483,8.基金项目
1.国家自然科学基金面上项目(No.82372585) （No.82372585）
2.广东省中医药局科研项目(No.20211365 （）
No.20223017) （）
3.佛山市自筹经费类科技创新项目(No.2220001005567) Supported by National Natural Science Foundation of China(General)(No.82372585),Guangdong Provincial Administration of Traditional Chinese Medicine Research Projects(No.20211365 （No.2220001005567）
No.20223017)and Foshan Self-funded Science and Technology Innovation Project(No.2220001005567) （No.2220001005567）
