中国口腔种植学杂志2025，Vol.30Issue(2)：127-134,8.DOI:10.12337/zgkqzzxzz.2025.04.006
富血小板纤维蛋白在上颌窦底提升中应用的研究进展
Advances in the application of platelet-rich fibrin in sinus floor elevation
摘要
Abstract
Sinus floor elevation is an effective procedure for addressing bone deficiency in the posterior maxillary region.To achieve an ideal three-dimensional osteogenesis model for the maxillary sinus(3D-OMMS),which involves coordinated bone formation along the maxillary sinus floor wall,Schneiderian membrane,and implant surface,improvements in surgical techniques combined with the rational use of biomaterials are required.Platelet-rich fibrin(PRF)not only releases various growth factors but also modulates local immune responses and promotes the proliferation of various cells,including stem cells.By harnessing the beneficial osteogenic potential from both the bone wound and the maxillary sinus membrane,PRF plays an active role in the 3D-OMMS.Therefore,it is recommended to use PRF in maxillary sinus floor elevation surgery.This review summarizes clinical evidence indicating that PRF alone,PRF combined with other biomaterials,and PRF utilized with the"tenting effect"of implants to elevate the Schneiderian membrane can all achieve stable outcomes in sinus floor elevation.Additionally,it offers a summary and recommendations for clinical decision-making regarding the use of PRF in sinus floor elevation procedures.关键词
上颌窦底提升/富血小板纤维蛋白/牙种植/骨再生Key words
Sinus floor elevation/Platelet-rich fibrin/Dental implants/Bone regeneration引用本文复制引用
吕慧欣,周延民..富血小板纤维蛋白在上颌窦底提升中应用的研究进展[J].中国口腔种植学杂志,2025,30(2):127-134,8.基金项目
国家自然科学基金(82371006) （82371006）
吉林省财政厅科技项目(jcsz2023481-5) National Natural Science Foundation of China(82371006) （jcsz2023481-5）
Jilin Provincial Department of Finance Science and Technology Project(jcsz2023481-5) （jcsz2023481-5）
