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成骨/破骨细胞轴对糖尿病骨代谢影响的研究进展

王子扬 马旭东

中国口腔种植学杂志2025,Vol.30Issue(2):176-179,4.
中国口腔种植学杂志2025,Vol.30Issue(2):176-179,4.DOI:10.12337/zgkqzzxzz.2025.04.012

成骨/破骨细胞轴对糖尿病骨代谢影响的研究进展

Research progress on the effects of osteoblast/osteoclast axis on bone metabolism in diabetes mellitus

王子扬 1马旭东1

作者信息

  • 1. 湖州师范学院医学院(护理学院) 313002,浙江
  • 折叠

摘要

Abstract

The osteoblast/osteoclast axis is a key regulatory system in bone metabolism,in which osteoblasts and osteoclasts interact and regulate each other through multiple signaling pathways to maintain skeletal homeostasis.Diabetes mellitus is a metabolic disease characterized by absolute or relative insulin deficiency,leading to impaired osseointegration and reduced success rates of implant therapy.This paper reviews the biological role of the osteoblast/osteoclast axis and the impact of diabetes mellitus on its regulation.It also discusses potential strategies for modulating this axis to enhance osseointegration in diabetic patients and improve the clinical success of implant treatment.

关键词

成骨/破骨细胞轴/糖尿病/骨结合/种植修复

Key words

Osteoblast/osteoclast axis/Diabetes mellitus/Osseointegration/Implant prosthesis

引用本文复制引用

王子扬,马旭东..成骨/破骨细胞轴对糖尿病骨代谢影响的研究进展[J].中国口腔种植学杂志,2025,30(2):176-179,4.

中国口腔种植学杂志

1007-3957

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