中国临床药理学杂志2025，Vol.41Issue(3)：433-437,5.DOI:10.13699/j.cnki.1001-6821.2025.03.027
中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状
Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia
摘要
Abstract
The transient receptor potential vanilloid subtype 1(TRPV1)signaling pathway is closely related to herpes zoster(HZ)and postherpetic neuralgia(PHN).Traditional Chinese medicine(TCM)has been involved in regulating the TRPV1 signaling pathway in several ways,and has been used to treat HZ and PHN by modulating the aberrant release of TRPV 1-associated neuropeptides and inflammatory factors,and neurogenic inflammatory response,etc.This paper summarizes the mechanism and role of TCM in regulating TRPV 1 signaling pathway in the treatment of HZ and PHN in recent years,which will provide new ideas for the treatment of HZ and PHN and drug development.关键词
中医药/带状疱疹及后遗神经痛/瞬时受体电位香草酸亚型1/炎症因子/皮肤神经源性炎症Key words
traditional Chinese medicine/herpes zoster and postherpetic neuralgia/transient receptor potential vanilloid subtype 1/inflammatory factor/neurogenic inflammation of the skin分类
医药卫生引用本文复制引用
谢小涛,牛凡琪,潘钰晶,何世烨,王思农,周文丽..中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状[J].中国临床药理学杂志,2025,41(3):433-437,5.基金项目
国家重点研发计划"中医药现代化研究"重点专项基金资助项目(2018YFC1705301、2018YFC1705302) （2018YFC1705301、2018YFC1705302）
