中国临床药理学杂志2025,Vol.41Issue(4):591-595,5.DOI:10.13699/j.cnki.1001-6821.2025.04.029
环泊酚的临床研究现状
Clinical research status of ciprofol
摘要
Abstract
Ciprofol is a type of innovative drug independently developed in China and with global independent intellectual property rights.It is a short-acting intravenous sedative based on the structural modification of propofol.It has the advantages of fast onset,fast recovery,high titer,good selectivity,low accumulation,stable respiratory circulation,and few adverse reactions,providing a better choice for clinical stable sedation and anesthesia,and has good clinical application potential.A series of clinical studies have evaluated the sedative effects of ciprofol in various procedures and settings,demonstrating its application in endoscopic sedation,general anesthesia,and sedation during intensive care.This paper reviewed the mechanism of action,pharmacokinetics and pharmacokinetic properties of ciprofol,and the progress of clinical application research,and evaluated the effectiveness and safety of ciprofol by synthesizing relevant clinical trial data.关键词
环泊酚/麻醉/药效动力学/药代动力学Key words
ciprofol/anesthesia/pharmacodynamics/pharmacokinetics分类
药学引用本文复制引用
江宇,侯文龙,杜建龙,宗酉明..环泊酚的临床研究现状[J].中国临床药理学杂志,2025,41(4):591-595,5.基金项目
嘉兴市级科学基金资助项目(022-sys-002) (022-sys-002)