中国临床药理学杂志2025，Vol.41Issue(5)：737-741,5.DOI:10.13699/j.cnki.1001-6821.2025.05.027
组学技术在中药防治子宫内膜异位症中的研究现状
Research status of histological techniques in traditional Chinese medicine for prevention and treatment of endometriosis
摘要
Abstract
The clinical efficacy of Chinese medicines in the prevention and treatment of endometriosis(EMs)is precise and can work through multiple pathways and targets.However,the complexity of the components of Chinese medicines and the single research method have led to slow progress in this field.With the emergence of high-throughput technologies,the limitations of single targets or pathways in interpreting the"holistic regulation"of TCM have been remedied by identifying genes associated with the pathophysiology of endometriosis.In this review,genomics,transcriptomics,proteomics,metabolomics,and their combinatorial techniques are reviewed to reveal the molecular mechanisms of Chinese herbal medicines in the prevention and treatment of endometriosis.It provides reference ideas for precise and objective revelation of prevention and treatment of EMs,as well as theoretical basis for revealing the mechanism of complex drug intervention in the disease.关键词
中药/子宫内膜异位症/多组学技术/作用机制/研究现状Key words
traditional Chinese medicine/endometriosis/multi-omics technology/mechanism of action/research status分类
医药卫生引用本文复制引用
岳斌,梁莉,褚翠君,万文文,陈元欢,黄灿灿,程渊,张小花,武权生,毛海燕..组学技术在中药防治子宫内膜异位症中的研究现状[J].中国临床药理学杂志,2025,41(5):737-741,5.基金项目
国家自然科学基金资助项目(81760879) （81760879）
国家自然科学基金地区科学基金资助项目(82260949) （82260949）
甘肃省自然科学基金资助项目(23JRRA1751、23JRRA1757) （23JRRA1751、23JRRA1757）
甘肃省中医药科研课题资助项目(GZKP-2023-21) （GZKP-2023-21）
甘肃省人民医院院内科研基金资助项目(23GSSYE-1) （23GSSYE-1）
甘肃省中医药研究中心开放课题资助项目(zyzx-2023-09) （zyzx-2023-09）
甘肃中医药大学人才引进基金资助项目(301/30140603) （301/30140603）
