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肿瘤微环境B细胞的研究现状与展望

陆泓雨 张生华 黄晶

中国免疫学杂志2025,Vol.41Issue(4):985-989,5.
中国免疫学杂志2025,Vol.41Issue(4):985-989,5.DOI:10.3969/j.issn.1000-484X.2025.04.035

肿瘤微环境B细胞的研究现状与展望

Research status and prospects of B cells in tumor microenvironment

陆泓雨 1张生华 1黄晶1

作者信息

  • 1. 北京大学医学部基础医学院免疫学系,北京 100191
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摘要

Abstract

Adaptive immune cells play an important role in tumor immunity.The function of T cells in tumor microenviron-ment has been studied in detail,but B cells needs to be further explored.Due to the different characteristics of producing antibodies,secreting cytokines,and presenting antigens,tumor-infiltrating B cells are divided into two phenotypes:promoting and inhibiting tu-mor proliferation.This study reviews the specific functions of B cells in the tumor microenvironment in order to explore the mechanisms of B cells involved in tumor immunity,which may provide a basis for the precision treatment targeting B cells in tumor.

关键词

肿瘤微环境/B细胞/免疫球蛋白

Key words

Tumor microenvironment/B cell/Immunoglobulin

分类

医药卫生

引用本文复制引用

陆泓雨,张生华,黄晶..肿瘤微环境B细胞的研究现状与展望[J].中国免疫学杂志,2025,41(4):985-989,5.

基金项目

国家自然科学基金面上项目(82171806). (82171806)

中国免疫学杂志

OA北大核心

1000-484X

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