中国免疫学杂志2025，Vol.41Issue(4)：1004-1009,6.DOI:10.3969/j.issn.1000-484X.2025.04.038
自噬在类风湿关节炎发病机制中的作用
Role of autophagy in pathogenesis of rheumatoid arthritis
摘要
Abstract
Rheumatoid arthritis(RA)is a systemic inflammatory disease characterized by erosive arthritis that can eventually lead to joint deformity and loss of function,which is unknown.Autophagy is a self-degradation process in which cells reuse internal proteins and organelles allowing organisms to withstand adverse situations such as starvation and infection,and eventually allowing cells to survive.In recent years,many studies have discovered that autophagy plays a role in the pathogenesis of RA,including the production of pannus,synovitis,bone degradation,and other critical pathological connections that influence RA progression and prog-nosis.This article examines the function of autophagy in the pathogenesis of RA,with the goal of generating new ideas for future RA treatment and drug development.关键词
类风湿关节炎/自噬/发病机制Key words
Rheumatoid arthritis/Autophagy/Pathogenesis分类
医药卫生引用本文复制引用
李丽萍,夏培哲,沈嫦娟,谢希..自噬在类风湿关节炎发病机制中的作用[J].中国免疫学杂志,2025,41(4):1004-1009,6.基金项目
国家自然科学基金(81873882). （81873882）
