枸杞多糖对镉致鸭大脑皮质氧化损伤的保护效应OA北大核心

In order to investigate the protective effect of Lycium barbarum polysaccharides(LBP)on cadmium(Cd)-induced oxidative damage of duck cerebral cortex,thirty-two 7-day-old Shaoxing laying ducks were randomly divided into four groups,the control group(Con),the LBP group,the cadmium group(Cd),and the co-treatment group of cadmium and LBP(Cd+LBP).Adaptive feeding for 10 days,the ducks in Con group was fed with basal diet.In Cd group,50 mg/kg cadmium chloride were added in the basal diet.In LBP group,50 mg/kg LBP were added in the basal diet.In LBP+Cd group,50 mg/kg cadmium chloride and 50 mg/kg LBP were added in the basal diet.The feeding period was 30 days.The T-AOC,T-SOD and CAT activi-ties,GSH and MDA contents in the duck cerebral cortex were determined.The results showed that compared with the Con group,T-SOD activity,GSH content and T-AOC were significantly reduced(P＜0.05),CAT ac-tivity and MDA content were significantly increased(P＜0.05)in the duck cerebral cortex of the Cd group.Compared with the Cd group,T-SOD activity,GSH content and T-AOC were increased significantly(P＜0.05),CAT activity and MDA content were significantly decreased(P＜0.05)in the duck cerebral cor-tex of the LBP+Cd group.The results indicated that LBP had a certain protective effect on Cd-induced oxidative damage of the duck cerebral cortex.