中国体外循环杂志2025，Vol.23Issue(2)：122-126,5.DOI:10.13498/j.cnki.chin.j.ecc.2025.02.07
改良超滤致循环系统进气原因分析与应对策略
Etiology analysis and management strategies for air embolism in circulatory systems during modified ultrafiltration
摘要
Abstract
Objective To investigate the etiology of air embolism in circulatory systems during modified ultrafiltration(MUF)and to propose prevention measures and management strategies.Methods We conducted a retrospective analysis of air embolism events during cardiopulmonary bypass(CPB)at Shanghai Children's Medical Center over a 12-year period.Data on causative factors,management approaches,and clinical outcomes were systematically evaluated.Results Among 34,519 CPB procedures performed between January 2013 and August 2024,18 cases(0.05%)of air embolism during MUF were identified.Human factors accounted for 9 cases(8 perfusionist errors,1 surgical error),while technical factors comprised the remaining 9 cases,all attributed to arterial cannula orifice proximity to the vessel wall,leading to wall suction during MUF.Clinical outcomes included transient neurological complications in 3 patients and 1 mortality,with no significant sequelae in the remaining cases.Conclusion Air embolism during MUF primarily results from human error and arterial wall suction by cannula orifices.Implementation of comprehensive training programs for cannulation and emergency management,rigorous intraoperative verification protocols,enhanced surgeon-perfusionist communication,and timely equipment maintenance can significantly reduce air embolism risks.Prompt and appropriate management strategies are crucial for minimizing complications.关键词
体外循环/改良超滤/不良事件/心脏手术Key words
Cardiopulmonary bypass/Modified ultrafiltration/Accident/Cardiac surgery引用本文复制引用
郭铮,张蔚,沈佳,姜磊,黄坚鹄,王伟..改良超滤致循环系统进气原因分析与应对策略[J].中国体外循环杂志,2025,23(2):122-126,5.基金项目
国家自然科学基金(82470417) （82470417）
