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体外膜氧合抗凝管理的新进展与挑战

徐恩慧 孙琦 卢娟 熊鹰 魏新广 刘燕

中国体外循环杂志2025,Vol.23Issue(2):176-180,185,6.
中国体外循环杂志2025,Vol.23Issue(2):176-180,185,6.DOI:10.13498/j.cnki.chin.j.ecc.2025.02.16

体外膜氧合抗凝管理的新进展与挑战

Recent advances and future perspectives in anticoagulation management for extracorporeal membrane oxygenation

徐恩慧 1孙琦 2卢娟 2熊鹰 2魏新广 2刘燕2

作者信息

  • 1. 430000 武汉,武汉科技大学附属武汉亚洲心脏病医院体外循环科||武汉科技大学医学部医学院
  • 2. 430000 武汉,武汉科技大学附属武汉亚洲心脏病医院体外循环科
  • 折叠

摘要

Abstract

During extracorporeal membrane oxygenation(ECMO),the goal of anticoagulation management is to prevent thrombus formation within the circuit,oxygenator,and the patient's body,as well as minimizing bleeding complications.Bleeding and thrombosis are common complications in ECMO therapy and are significantly associated with increased mortality and adverse outcomes.Anticoagulation is essential for maintaining ECMO circuit patency and preventing thromboembolic complications but also contributes to bleeding complications.How to reduce bleeding while preventing thrombus formation has become one of the primary challenges in ECMO support.Therefore,monitoring coagulation status and implementing anticoagulation strategies during ECMO support are particularly critical.This article reviews the latest research progress on anticoagulation strategies and monitoring during ECMO and explores the challenges currently faced in ECMO treatment.

关键词

体外膜氧合/抗凝/抗凝管理/监测/进展

Key words

Extracorporeal membrane oxygenation/Anticoagulation/Complications/Monitoring/Anticoagulation management

引用本文复制引用

徐恩慧,孙琦,卢娟,熊鹰,魏新广,刘燕..体外膜氧合抗凝管理的新进展与挑战[J].中国体外循环杂志,2025,23(2):176-180,185,6.

基金项目

湖北省卫生健康委员会2021指导性项目(WJ2021F018) (WJ2021F018)

2023年武汉市医学科学研究项目(WX23A76) (WX23A76)

中国体外循环杂志

1672-1403

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