中国体外循环杂志2025,Vol.23Issue(2):176-180,185,6.DOI:10.13498/j.cnki.chin.j.ecc.2025.02.16
体外膜氧合抗凝管理的新进展与挑战
Recent advances and future perspectives in anticoagulation management for extracorporeal membrane oxygenation
摘要
Abstract
During extracorporeal membrane oxygenation(ECMO),the goal of anticoagulation management is to prevent thrombus formation within the circuit,oxygenator,and the patient's body,as well as minimizing bleeding complications.Bleeding and thrombosis are common complications in ECMO therapy and are significantly associated with increased mortality and adverse outcomes.Anticoagulation is essential for maintaining ECMO circuit patency and preventing thromboembolic complications but also contributes to bleeding complications.How to reduce bleeding while preventing thrombus formation has become one of the primary challenges in ECMO support.Therefore,monitoring coagulation status and implementing anticoagulation strategies during ECMO support are particularly critical.This article reviews the latest research progress on anticoagulation strategies and monitoring during ECMO and explores the challenges currently faced in ECMO treatment.关键词
体外膜氧合/抗凝/抗凝管理/监测/进展Key words
Extracorporeal membrane oxygenation/Anticoagulation/Complications/Monitoring/Anticoagulation management引用本文复制引用
徐恩慧,孙琦,卢娟,熊鹰,魏新广,刘燕..体外膜氧合抗凝管理的新进展与挑战[J].中国体外循环杂志,2025,23(2):176-180,185,6.基金项目
湖北省卫生健康委员会2021指导性项目(WJ2021F018) (WJ2021F018)
2023年武汉市医学科学研究项目(WX23A76) (WX23A76)