中国医学创新2025,Vol.22Issue(10):175-178,4.DOI:10.3969/j.issn.1674-4985.2025.10.041
华蟾素调控结直肠癌肿瘤微环境的研究进展
Research Progress of Cinobufagin in Regulating Tumor Microenvironment of Colorectal Cancer
摘要
Abstract
Colorectal cancer(CRC)is one of the most common malignant tumors in the digestive system.Its occurrence and development not only depend on tumor parenchyma,but also is closely related to its survival environment,the tumor microenvironment(TME).With the deepening of anti-tumor research targeting TME,more and more studies have found that the treatment targeting TME has significant advantages,and Cinobufotalin can achieve anti-tumor effect by influencing TME.This article mainly reviews the effects of common components of tumor associated macrophages(TAMs)and T cells in CRC TME and Cinobufotalin on CRC TME.关键词
结直肠癌/华蟾素/肿瘤微环境Key words
Colorectal cancer/Cinobufagin/Tumor microenvironment引用本文复制引用
刘新辰,张子璇,周雅娟,刘晓东,尹茂续,孙磊昱,杨丽娟..华蟾素调控结直肠癌肿瘤微环境的研究进展[J].中国医学创新,2025,22(10):175-178,4.基金项目
山东省2019-2020年度中医药科技发展计划项目(2019-0517) (2019-0517)