中国医学创新2025，Vol.22Issue(11)：34-37,4.DOI:10.3969/j.issn.1674-4985.2025.11.008
经鼻高流量湿化氧疗联合布地奈德治疗急性呼吸衰竭患者的效果
Effect of Nasal High-flow Humidification Oxygen Therapy Combined with Budesonide on Patients with Acute Respiratory Failure
摘要
Abstract
Objective:To investigate the effect of nasal high-flow humidification oxygen therapy combined with Budesonide Inhalation Aerosol on patients with acute respiratory failure.Method:The clinical data of 72 patients with acute respiratory failure admitted to Xinyu Iron and Steel Group Co.,LTD.Central Hospital from July 2021 to July 2023 were retrospectively analyzed.The patients were divided into different groups according to different treatment methods.36 patients treated with Budesonide Inhalation Aerosol were used as control group,and 36 patients treated with Budesonide Inhalation Aerosol plus nasal high-flow humidification oxygen therapy were used as observation group.Vital signs,oxygenation,respiratory dynamics,acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score and adverse reactions were compared between the two groups.Result:After treatment,the heart rate,diastolic blood pressure,systolic blood pressure,airway resistance,mean airway pressure,arterial partial pressure of carbon dioxide(PaCO2)and APACHE Ⅱ score in the observation group were lower than those in the control group,arterial partial pressure of oxygen(PaO2),oxygen saturation of blood(SaO2),oxygenation index(OI)were higher than those of control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The application of nasal high-flow humidification oxygen therapy combined with Budesonide Inhalation Aerosol in the treatment of acute respiratory failure can improve the vital signs of patients,regulate the respiratory function and oxygenation status of the body,and have high safety.关键词
急性呼吸衰竭/布地奈德吸入气雾剂/经鼻高流量湿化氧疗/氧合指数/急性生理与慢性健康评估Ⅱ评分Key words
Acute respiratory failure/Budesonide Inhalation Aerosol/Nasal high-flow humidified oxygen therapy/Oxygenation index/Acute physiology and chronic health evaluation Ⅱ score引用本文复制引用
傅雷玉,胡苗苗,张婷..经鼻高流量湿化氧疗联合布地奈德治疗急性呼吸衰竭患者的效果[J].中国医学创新,2025,22(11):34-37,4.基金项目
新余市科技计划项目(20223090951) （20223090951）
