中国医学创新2025，Vol.22Issue(11)：38-42,5.DOI:10.3969/j.issn.1674-4985.2025.11.009
硫普罗宁联合恩替卡韦治疗慢性乙型肝炎的临床效果
Clinical Effect of Tiopronin Combined with Entecavir in the Treatment of Chronic Hepatitis B
章恒 1朱正欣 2朱正为3
作者信息
- 1. 上饶市第二人民医院消化内科 江西 上饶 334000
- 2. 上饶市人民医院影像科 江西 上饶 334000
- 3. 上饶市人民医院老年医学科 江西 上饶 334000
- 折叠
摘要
Abstract
Objective:To explore the clinical effect of Tiopronin combined with Entecavir in the treatment of chronic hepatitis B.Method:A total of 80 patients with chronic hepatitis B admitted to Shangrao Second People's Hospital from May 2022 to April 2024 were selected and divided into two groups according to random number method,with 40 cases in each group.The control group was given Entecavir,and the observation group was given Tiopronin on the basis of control group.The clinical efficacy,liver function,liver fibrosis indexes,inflammatory factors and adverse reactions were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).After treatment,the liver function,liver fibrosis and inflammatory factors indexes levels in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Tiopronin combined with Entecavir in the treatment of chronic hepatitis B has definite clinical effect,can improve patients'liver function and reduce inflammatory reaction,and has good safety.关键词
硫普罗宁/恩替卡韦/慢性乙型肝炎/肝纤维化/肝功能/不良反应Key words
Tiopronin/Entecavir/Chronic hepatitis B/Liver fibrosis/Liver function/Adverse reactions引用本文复制引用
章恒,朱正欣,朱正为..硫普罗宁联合恩替卡韦治疗慢性乙型肝炎的临床效果[J].中国医学创新,2025,22(11):38-42,5.
