中国医学创新2025，Vol.22Issue(11)：90-94,5.DOI:10.3969/j.issn.1674-4985.2025.11.020
中药熏蒸联合艾灸对血液透析患者自体动静脉内瘘成熟率及内瘘功能不良的临床研究及作用机制
Clinical Study and Mechanism of Traditional Chinese Medicine Fumigation Combined with Moxibustion on Maturation Rate of Autologous Arteriovenous Fistula and Internal Fistula Dysfunction in Hemodialysis Patients
摘要
Abstract
Objective:To analyze the effect of traditional Chinese medicine fumigation combined with moxibustion on the function of autogenous arteriovenous fistula in hemodialysis patients.Method:A total of 90 hemodialysis patients with chronic kidney disease who were established with autologous arteriovenous fistula in the Second People's Hospital of Jingdezhen from March 2023 to January 2024 were selected and divided into group A(n=30,received routine intervention),group B(n=30,received routine intervention and traditional Chinese medicine fumigation)and group C(n=30,received traditional Chinese medicine fumigation combined with moxibustion on the basis of group A)by random number table method.The internal fistula maturity,internal fistula function,inflammatory factors,vasoactive factors and the incidence of internal hypercoageulation and fistula dysfunction were compared among the three groups.Result:After intervention,there were statistically significant differences in internal fistula diameter,internal fistula blood flow among the three groups(P<0.05).After intervention,the internal fistula diameter and internal fistula blood flow in group C were greater than those in group B and group A,those in group B were greater than those in group A(P<0.05).The maturity time of internal fistula in group C was earlier than that in group B and group A,and that in group B was earlier than that in group A,the differences were statistically significant(P<0.05).The rate of fistula maturation in group C was higher than that in group B and group A(P<0.05).After intervention,the blood flow during dialysis and arterial end pressure in group C were higher than those in group B and group A,those in group B were higher than those in group A,and the venous end pressure in group C was lower than that in group B and A,and that in group B was lower than that in group A,the differences were statistically significant(P<0.05).After intervention,there were statistically significant differences in interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and vascular endothelial growth factor-A(VEGF-A)among three groups(P<0.05).After intervention,IL-6,TNF-α and VEGF-A in group C were lower than those in group B and group A,and those in group B were lower than those in group A,the differences were statistically significant(P<0.05).The incidence of hypercoagulation in group C was lower than that in group A(P<0.05).The incidence of internal fistula dysfunction among the three groups was statistically significant(P<0.05).The incidence of internal fistula dysfunction in group C was significantly lower than that in group A,the difference was statistically significant(P<0.05).Conclusion:Traditional Chinese medicine fumigation combined with moxibustion can promote the maturation of autologous arteriovenous fistula in hemodialysis patients,improve the function of internal fistula,and reduce the incidence of internal fistula dysfunction.关键词
血液透析/自体动静脉内瘘/中药熏蒸/艾灸/内瘘成熟/内瘘功能不良Key words
Hemodialysis/Autologous arteriovenous fistula/Traditional Chinese medicine fumigation/Moxibustion/Internal fistula maturation/Internal fistula dysfunction引用本文复制引用
周敏,朱小红,江新爱..中药熏蒸联合艾灸对血液透析患者自体动静脉内瘘成熟率及内瘘功能不良的临床研究及作用机制[J].中国医学创新,2025,22(11):90-94,5.基金项目
江西省中医药管理局科技计划项目(2023B0915) （2023B0915）
